METHODS: In this study, we aimed to investigate the potential advantages and disadvantages of isotretinoin as a treatment for FFA. To identify all relevant articles, we developed a comprehensive search strategy and conducted a thorough search of three major databases: PubMed, Embase, and Science Direct. We retrieved a total of 82 articles from the search results. Two independent reviewers then screened each of the 82 articles based on our inclusion and exclusion criteria, resulting in the identification of 15 articles that were deemed relevant to our study.
RESULTS: Across the 15 articles, 232 patients who suffered from FFA were involved. Nearly 90% of patients experienced a significant reduction of symptoms after receiving oral isotretinoin at 10-40 mg daily. We conclude that isotretinoin can positively affect facial papules and help suppress hair loss.
方法:在本研究中,我们旨在探讨异维A酸作为FFA治疗的潜在优势和劣势.为了识别所有相关文章,我们制定了全面的搜索策略,并对三个主要数据库进行了彻底的搜索:PubMed,Embase,科学直接。从搜索结果中,我们共检索到82篇文章。然后,两名独立审稿人根据我们的纳入和排除标准对82篇文章中的每一篇进行了筛选,结果确定了15篇被认为与我们的研究相关的文章。
结果:在15篇文章中,232名患有FFA的患者参与其中。近90%的患者在接受每日10-40mg的口服异维A酸后症状显着减轻。我们得出的结论是,异维A酸可以积极影响面部丘疹并有助于抑制脱发。