Abstract：
Desmoplastic fibroma (DF) is a rare benign bone tumor adopting an aggressive behavior, representing a challenge for clinical and radiographic diagnosis. This case report focused on a 31-year-old man with a large mandibular lesion with severe displacements of the mandibular teeth. Only a combination of paraclinical findings allows a definitive diagnosis to be made. Cervicofacial MRI revealed a low T1 signal intensity with peripheral enhancement after Gadolinium, and T2 hyperintense signal, while PET scan showed a moderate metabolism. Bone biopsy with immunohistochemical analysis allowed for definitive diagnosis of DF after eliminating the main differential diagnosis (fibrous dysplasia, fibrosarcoma, desmoid tumor, and osteosarcoma). The patient was successfully treated by large mandibular resection and reconstruction with a free-fibular bone flap\".
摘要：
纤维增生性纤维瘤（DF）是一种罕见的良性骨肿瘤，采用攻击行为，代表了临床和影像学诊断的挑战。此病例报告集中于一名31岁的男子，该男子下颌病变较大，下颌牙齿严重移位。只有副临床发现的组合才能做出明确的诊断。颈面部MRI显示低T1信号强度，钆后周围增强，和T2高强度信号，而PET扫描显示中等代谢。骨活检和免疫组织化学分析允许在消除主要鉴别诊断后明确诊断DF（纤维发育不良，纤维肉瘤,硬纤维瘤，和骨肉瘤）。该患者通过下颌骨大切除和游离腓骨骨瓣重建成功治疗。”
