关键词: Lymph node metastasis Lymphadenectomy Retroperitoneal lymph node dissection Retroperitoneal lymph nodes Testicular cancer

Mesh : Male Humans Testicular Neoplasms / drug therapy Retroperitoneal Space / pathology surgery Lymph Node Excision / methods Lymph Nodes / surgery pathology Neoplasms, Germ Cell and Embryonal / surgery pathology Retrospective Studies Treatment Outcome Neoplasm Staging

来  源:   DOI:10.1007/s11912-024-01511-y   PDF(Pubmed)

Abstract:
This narrative review provides a comprehensive overview of the evolving role of retroperitoneal lymph node dissection (RPLND) in the management of testicular cancer (TC). It explores the significance of RPLND as both a diagnostic and therapeutic tool, highlighting its contribution to accurate staging, its impact on oncological outcomes, and its influence on subsequent treatment decisions.
RPLND serves as an essential diagnostic procedure, aiding in the precise assessment of lymph node involvement and guiding personalized treatment strategies. It has demonstrated therapeutic value, particularly in patients with specific risk factors and disease stages, contributing to improved oncological outcomes and survival rates. Recent studies have emphasized the importance of meticulous patient selection and nerve-sparing techniques to mitigate complications while optimizing outcomes. Additionally, modern imaging and surgical approaches have expanded the potential applications of RPLND. In the context of TC management, RPLND remains a valuable and evolving tool. Its dual role in staging and therapy underscores its relevance in contemporary urological practice. This review highlights the critical role of RPLND in enhancing patient care and shaping treatment strategies, emphasizing the need for further research to refine patient selection and surgical techniques.
摘要:
目的:这篇叙述性综述全面概述了腹膜后淋巴结清扫术(RPLND)在睾丸癌(TC)治疗中的作用。它探讨了RPLND作为诊断和治疗工具的重要性,强调它对准确分期的贡献,它对肿瘤结果的影响,及其对后续治疗决策的影响。
结果:RPLND是必不可少的诊断程序,有助于精确评估淋巴结受累情况并指导个性化治疗策略。它已经证明了治疗价值,特别是在具有特定风险因素和疾病阶段的患者中,有助于改善肿瘤学结果和生存率。最近的研究强调了精心选择患者和保留神经技术的重要性,以减轻并发症,同时优化结果。此外,现代影像学和手术方法扩大了RPLND的潜在应用。在TC管理的背景下,RPLND仍然是一个有价值的和不断发展的工具。它在分期和治疗中的双重作用强调了它在当代泌尿外科实践中的相关性。这篇综述强调了RPLND在加强患者护理和制定治疗策略方面的关键作用。强调需要进一步研究以完善患者选择和手术技术。
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