Abstract：
While inpatient withdrawal management/acute stabilization can improve outcomes for individuals with opioid use disorder (OUD), patients often leave treatment early due to mood, tension, and cravings associated with opioid withdrawal. The aim of this study was to evaluate the feasibility and preliminary effectiveness of a novel virtual reality (VR) based intervention; 3D Therapy Thrive (3DTT).
Subjects with OUD (N = 32) were recruited from a community acute stabilization program and received up to two sessions of 3DTT. They completed questionnaires related to their overall satisfaction with the experience and side effects; as well as those related to mood, tension, and cravings.
There were no reported side effects and the majority of subjects (94%) reported high satisfaction with the experience. Out of 62 patients approached, 33 patients agreed to participate (53%) 33 patients completed one, and 17 of these patients (52%) completed both sessions of 3DTT, with 19 participants (58%) completing their treatment protocols. Compared to baseline, 3DTT participants reported significant reductions in depression, tension, and cravings (p\'s < 0.001).
This pilot study supports the feasibility and preliminary effectiveness of 3DTT for improving outcomes for inpatients with OUD. Future randomized controlled trials are necessary to evaluate the efficacy of 3DTT for improving retention, reducing cravings, and improving mood and tension.
This is the first study to evaluate the feasibility of a psychologically informed VR intervention in inpatients with OUD.
Subjects with OUD (N = 32) were recruited from a community acute stabilization program and received up to two sessions of 3DTT. They completed questionnaires related to their overall satisfaction with the experience and side effects; as well as those related to mood, tension, and cravings.
There were no reported side effects and the majority of subjects (94%) reported high satisfaction with the experience. Out of 62 patients approached, 33 patients agreed to participate (53%) 33 patients completed one, and 17 of these patients (52%) completed both sessions of 3DTT, with 19 participants (58%) completing their treatment protocols. Compared to baseline, 3DTT participants reported significant reductions in depression, tension, and cravings (p\'s < 0.001).
This pilot study supports the feasibility and preliminary effectiveness of 3DTT for improving outcomes for inpatients with OUD. Future randomized controlled trials are necessary to evaluate the efficacy of 3DTT for improving retention, reducing cravings, and improving mood and tension.
This is the first study to evaluate the feasibility of a psychologically informed VR intervention in inpatients with OUD.
摘要：
目的：虽然住院戒断管理/急性稳定可以改善阿片类药物使用障碍（OUD）患者的预后，患者经常因情绪而提前离开治疗，紧张,以及与阿片类药物戒断相关的渴望。这项研究的目的是评估基于新型虚拟现实（VR）的干预的可行性和初步有效性；3DTherapyThrive（3DTT）。
方法：OUD患者（N=32）从社区急性稳定计划中招募，并接受了多达两次的3DTT治疗。他们完成了与他们对体验和副作用的总体满意度相关的问卷;以及与情绪相关的问卷，紧张,和渴望。
结果：没有报告的副作用，大多数受试者（94%）报告的经验满意度很高。在接受治疗的62名患者中，33名患者同意参加（53％）33名患者完成了一项，这些患者中有17名（52%）完成了两次3DTT，19名参与者（58％）完成了他们的治疗方案。与基线相比，3DTT参与者报告抑郁症显著减少，紧张,和渴望（p<0.001）。
结论：本初步研究支持3DTT改善OUD住院患者预后的可行性和初步有效性。未来的随机对照试验是必要的，以评估3DTT的疗效，以改善保留，减少渴望，改善情绪和紧张。
结论：这是第一项评估OUD住院患者心理知情VR干预可行性的研究。
方法：OUD患者（N=32）从社区急性稳定计划中招募，并接受了多达两次的3DTT治疗。他们完成了与他们对体验和副作用的总体满意度相关的问卷;以及与情绪相关的问卷，紧张,和渴望。
结果：没有报告的副作用，大多数受试者（94%）报告的经验满意度很高。在接受治疗的62名患者中，33名患者同意参加（53％）33名患者完成了一项，这些患者中有17名（52%）完成了两次3DTT，19名参与者（58％）完成了他们的治疗方案。与基线相比，3DTT参与者报告抑郁症显著减少，紧张,和渴望（p<0.001）。
结论：本初步研究支持3DTT改善OUD住院患者预后的可行性和初步有效性。未来的随机对照试验是必要的，以评估3DTT的疗效，以改善保留，减少渴望，改善情绪和紧张。
结论：这是第一项评估OUD住院患者心理知情VR干预可行性的研究。
