关键词: Elephantiasis neuromatosa Infected neurofibroma Negative pressure wound therapy Neurofibromatosis Plexiform neurofibroma

来  源:   DOI:10.1016/j.ijscr.2024.109428   PDF(Pubmed)

Abstract:
UNASSIGNED: Neurofibromatosis type 1 is a benign peripheral nerve tumor, often manifests as plexiform neurofibroma that may cause severe dysfunction, pain, and disfigurement. Bleeding has been reported as a complication of plexiform neurofibroma due to vascular fragility and vasculopathy that may develop into life-threatening bleeding especially after excision procedure. Consequently, post excision complications also include dehiscence and infection.
METHODS: We report a 23-year-old male with elephantiasis of the left lower extremity due to giant plexiform neurofibroma who underwent preoperative embolization followed by serial surgical mass reduction. There were postoperative complications consisting of hematoma, wound dehiscence, and infection.
UNASSIGNED: Negative pressure wound therapy is often used to accelerate wound healing, including infected wounds. However, negative pressure wound therapy has been a debatable modality for wound care of neurofibroma due to reported risks of profuse bleeding during its use.
CONCLUSIONS: In this case, despite the size, negative-pressure wound therapy has shown good results for infected neurofibroma wounds and as an adjunct as wound dressing for defect closure of neurofibroma with split-thickness skin graft.
摘要:
1型神经纤维瘤病是一种良性外周神经肿瘤,通常表现为丛状神经纤维瘤,可能导致严重的功能障碍,疼痛,和毁容。据报道,由于血管脆性和血管病变,出血是丛状神经纤维瘤的并发症,尤其是在切除手术后,出血可能会危及生命。因此,术后并发症还包括裂开和感染。
方法:我们报告了一名23岁的男性,由于巨大的丛状神经纤维瘤而导致左下肢象皮病,他接受了术前栓塞,然后进行了连续的手术切除。术后并发症包括血肿,伤口裂开,和感染。
负压伤口疗法通常用于加速伤口愈合,包括感染的伤口.然而,由于据报道在使用期间存在大量出血的风险,负压伤口治疗对于神经纤维瘤的伤口护理一直是有争议的方式。
结论:在这种情况下,尽管大小,负压伤口治疗对感染的神经纤维瘤伤口显示出良好的效果,并作为伤口敷料的辅助手段,用于通过分层厚度的皮肤移植物闭合神经纤维瘤的缺损。
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