Abstract:
Low-grade myofibroblastic sarcoma (LGMS) is a rare soft-tissue malignant neoplasm originating from the stromal cells that is predominantly comprised of atypical myofibroblasts. The present study reports the case of a patient with low-grade myofibroblastic sarcoma in the soft tissue of the knee. The patient exhibited a soft, painless mass on the medial side of the left knee. During surgery, a yellow-white mass above the posterior margin of the sartorius muscle was identified. This mass, which was irregular and adherent to surrounding tissues, had a blurry boundary, indicative of invasive growth. The morphology of the mass significantly differed from conventional lipomas and was lacking typical features. Immunohistochemical staining confirmed the diagnosis of a malignant LGMS. The patient experienced no recurrence over 1 year of follow-up and reported complete recovery of knee range of motion. The present study suggests that an incisional biopsy may be performed if LGMS is suspected based on patient symptoms and imaging results. In addition, long-term follow-up is crucial for the timely detection and management of any recurrence, playing a key role in the patient\'s ongoing care and treatment.
摘要:
低级肌纤维母细胞肉瘤(LGMS)是一种罕见的软组织恶性肿瘤,起源于基质细胞,主要由非典型肌成纤维细胞组成。本研究报告了一例膝盖软组织中低级别肌纤维母细胞肉瘤的患者。病人表现出一种柔软的,左膝盖内侧无痛肿块。手术期间,发现缝匠肌后缘上方有一个黄白色肿块。这个质量,不规则且粘附于周围组织,边界模糊,指示侵袭性生长。肿块的形态与常规脂肪瘤明显不同,缺乏典型特征。免疫组织化学染色证实了恶性LGMS的诊断。患者在1年的随访中没有复发,并报告膝关节活动范围完全恢复。本研究表明,如果根据患者症状和影像学结果怀疑LGMS,则可以进行切开活检。此外,长期随访对于及时发现和管理任何复发至关重要,在患者的持续护理和治疗中发挥关键作用。