PDF(Pubmed)
Abstract：
Haemophagocytic lymphohistiocytosis secondary to Histoplasma infection is rare and almost always occurs in immunocompromised hosts. We report a 32-year-old immunocompetent man presenting with a nonspecific febrile illness found to have disseminated histoplasmosis and associated haemophagocytic lymphohistiocytosis. The diagnosis was confirmed on histopathological examination and PCR of liver and bone marrow biopsies. He was successfully treated with steroids, intravenous immunoglobulin and itraconazole.
摘要：
继发于组织胞浆感染的噬血细胞性淋巴组织细胞增多症很少见，几乎总是发生在免疫受损的宿主中。我们报告了一名32岁的有免疫能力的人，患有非特异性发热性疾病，发现其已播散性组织胞浆菌病和相关的噬血细胞淋巴组织细胞增多症。通过组织病理学检查和肝和骨髓活检的PCR证实了诊断。他成功地接受了类固醇治疗,静脉注射免疫球蛋白和伊曲康唑。
