Abstract：
OBJECTIVE: To compare the safety and efficacy of micropulse laser (MP-TSCP) and slow coagulation transscleral cyclophotocoagulation (TSCP) with a diode laser for reducing intraocular pressure (IOP) in patients with refractory childhood glaucoma (CG).
METHODS: Patients with CG and at least 12 months of medical chart data were included. Data on preoperative and postoperative outcomes were analyzed. The primary outcomes were an IOP of 6-21 mmHg and/or ≥ 20% reduction in the baseline value.
RESULTS: A total of 17 eyes were included. The preoperative mean IOP was 28 mmHg in the MP-TSCP and 29.9 mmHg in the TSCP. The mean IOP decreased significantly to 17.26 ± 3.27 mmHg in the MP-TSCP and 14.68 ± 5.79 mmHg TSCP at the last medical record. Three anti-glaucoma meds were administered to the eyes preoperatively in both groups. A mean of 1.02 eye drops was administered to the MP-TSCP and 2.06 to the TSCP. The number of medications decreased by 2.38 ± 1.55 in the MP-TSCP and 0.82 ± 1.68 in the TSCP. The median preoperative visual acuity (logMAR) was 1.51 ± 1.06 in the MP-TSCP and 1.87 ± 0.74 in the TSCP. The variation in mean visual acuity (logMAR) was -0.027 ± 0.05 in the MP-TSCP and -0.40 ± 0.58 in the TSCP. The most frequent complication was corneal decompensation (one - MP-TSCP and two - TSCP).
CONCLUSIONS: Both techniques were effective and relatively safe for reducing IOP. These techniques appear to extend the indications of cyclophotocoagulation in CG eyes and improve the functional prognosis.
METHODS: Patients with CG and at least 12 months of medical chart data were included. Data on preoperative and postoperative outcomes were analyzed. The primary outcomes were an IOP of 6-21 mmHg and/or ≥ 20% reduction in the baseline value.
RESULTS: A total of 17 eyes were included. The preoperative mean IOP was 28 mmHg in the MP-TSCP and 29.9 mmHg in the TSCP. The mean IOP decreased significantly to 17.26 ± 3.27 mmHg in the MP-TSCP and 14.68 ± 5.79 mmHg TSCP at the last medical record. Three anti-glaucoma meds were administered to the eyes preoperatively in both groups. A mean of 1.02 eye drops was administered to the MP-TSCP and 2.06 to the TSCP. The number of medications decreased by 2.38 ± 1.55 in the MP-TSCP and 0.82 ± 1.68 in the TSCP. The median preoperative visual acuity (logMAR) was 1.51 ± 1.06 in the MP-TSCP and 1.87 ± 0.74 in the TSCP. The variation in mean visual acuity (logMAR) was -0.027 ± 0.05 in the MP-TSCP and -0.40 ± 0.58 in the TSCP. The most frequent complication was corneal decompensation (one - MP-TSCP and two - TSCP).
CONCLUSIONS: Both techniques were effective and relatively safe for reducing IOP. These techniques appear to extend the indications of cyclophotocoagulation in CG eyes and improve the functional prognosis.
摘要：
目的：比较微脉冲激光（MP-TSCP）与二极管激光慢凝经巩膜睫状体光凝（TSCP）对难治性儿童青光眼（CG）患者降低眼压（IOP）的安全性和有效性。
方法：纳入了CG患者和至少12个月的病历数据。对术前和术后结果数据进行分析。主要结果是眼压为6-21mmHg和/或基线值降低≥20%。
结果：共纳入17只眼。MP-TSCP术前平均IOP为28mmHg，TSCP术前平均IOP为29.9mmHg。MP-TSCP中的平均IOP显着降低至17.26±3.27mmHg，最后一次病历中的平均IOP降低至14.68±5.79mmHg。两组术前均对眼睛给予三种抗青光眼药物。向MP-TSCP施用平均1.02滴眼液,向TSCP施用平均2.06滴眼液。MP-TSCP中的药物数量减少了2.38±1.55，TSCP中的药物数量减少了0.82±1.68。MP-TSCP的术前视力中位数（logMAR）为1.51±1.06，TSCP为1.87±0.74。MP-TSCP的平均视敏度（logMAR）变化为-0.027±0.05，TSCP为-0.40±0.58。最常见的并发症是角膜代偿失调（1-MP-TSCP和2-TSCP）。
结论：这两种技术对降低眼压均有效且相对安全。这些技术似乎扩展了CG眼中睫状体光凝术的适应症并改善了功能预后。
方法：纳入了CG患者和至少12个月的病历数据。对术前和术后结果数据进行分析。主要结果是眼压为6-21mmHg和/或基线值降低≥20%。
结果：共纳入17只眼。MP-TSCP术前平均IOP为28mmHg，TSCP术前平均IOP为29.9mmHg。MP-TSCP中的平均IOP显着降低至17.26±3.27mmHg，最后一次病历中的平均IOP降低至14.68±5.79mmHg。两组术前均对眼睛给予三种抗青光眼药物。向MP-TSCP施用平均1.02滴眼液,向TSCP施用平均2.06滴眼液。MP-TSCP中的药物数量减少了2.38±1.55，TSCP中的药物数量减少了0.82±1.68。MP-TSCP的术前视力中位数（logMAR）为1.51±1.06，TSCP为1.87±0.74。MP-TSCP的平均视敏度（logMAR）变化为-0.027±0.05，TSCP为-0.40±0.58。最常见的并发症是角膜代偿失调（1-MP-TSCP和2-TSCP）。
结论：这两种技术对降低眼压均有效且相对安全。这些技术似乎扩展了CG眼中睫状体光凝术的适应症并改善了功能预后。
