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Abstract：
To investigate and compare the facial asymmetry (hard and soft tissues) among skeletal Class I, II, and III patients. A total of 221 subjects, including skeletal Class I (n = 80), skeletal Class II (n = 75), and skeletal Class III (n = 66), were included in the study. CBCT, 22 skeletal landmarks, and 10 soft tissue landmarks were used for the measurements and the asymmetry index was calculated to assess the facial asymmetry. Statistical analyses included one-way ANOVA, Kruskal-Wallis test, and Spearman correlation analysis. The skeletal Class III patients presented greater asymmetry than Class II patients for 10 hard tissue landmarks and 3 soft tissue landmarks (p < 0.05). High correlation of asymmetry was found between four soft tissue landmarks and their corresponding skeletal landmarks (rs ≥ 0.71), as well as Me and ANS (r > 0.86). The ANS and Me in 21.3% patients deviated to contralateral sides. The skeletal Class III patients had more facial asymmetry than the Class II patients. Soft tissues showed similar asymmetry as the underlying hard tissues rather than a compensation of the hard tissue asymmetry. The inconsistency in the deviation of Me and ANS may exacerbate facial asymmetry.
摘要：
为了研究和比较骨骼I类之间的面部不对称（硬组织和软组织），II,III患者。共221个科目，包括骨骼I类（n=80），骨骼II类（n=75），和骨骼III类（n=66），包括在研究中。CBCT,22个骨骼地标，并使用10个软组织标志进行测量，并计算不对称指数以评估面部不对称。统计分析包括单向方差分析，Kruskal-Wallis测试,和Spearman相关分析。对于10个硬组织标志和3个软组织标志，骨骼III类患者比II类患者表现出更大的不对称性（p<0.05）。4个软组织标志与其对应的骨骼标志高度相关（rs≥0.71），以及我和ANS（r>0.86）。21.3%的患者ANS和Me偏向对侧。骨骼III类患者的面部不对称程度高于II类患者。软组织显示出与底层硬组织相似的不对称性，而不是对硬组织不对称性的补偿。Me和ANS偏差的不一致可能加剧面部不对称。
