Abstract：
Neutrophilic urticarial dermatosis (NUD) is a rare form of dermatosis that is poorly understood. It was first described by Kieffer and colleagues as an urticarial eruption that is histopathologically characterized by a perivascular and interstitial neutrophilic infiltrate with intense leukocytoclasia and without vasculitis or dermal edema. NUD clinically presents as a chronic or recurrent eruption that consists of nonpruritic macules, papules, or plaques that are pink to reddish and that resolve within 24 hours without residual pigmentation. NUD is often associated with systemic diseases such as Schnitzler syndrome, lupus erythematosus, adult-onset Still\'s disease, and cryopyrin-associated periodic syndromes.
摘要：
中性粒细胞性荨麻疹皮肤病（NUD）是一种罕见的皮肤病，人们对此知之甚少。Kieffer及其同事首先将其描述为荨麻疹，其组织病理学特征是血管周围和间质嗜中性粒细胞浸润，伴有强烈的白细胞扩张，没有血管炎或皮肤水肿。NUD临床上表现为慢性或复发性喷发，包括非瘙痒性黄斑，丘疹,或粉红色至红色的斑块，并在24小时内消退，没有残留的色素沉着。NUD通常与全身性疾病相关，如Schnitzler综合征，红斑狼疮,成人发作的斯蒂尔病，和冷冻比林相关的周期性综合征。
