关键词: Histiocytoid sweet syndrome Leukemia cutis Myelodysplasia cutis Myelodysplastic syndrome Myeloid dermatoses Neutrophilic dermatosis Sweet syndrome

Mesh : Humans Sweet Syndrome / diagnosis Skin / pathology Myelodysplastic Syndromes / complications diagnosis pathology Biopsy

来  源:   DOI:10.1016/j.det.2023.08.004

Abstract:
In 2005, a new histologic variant of Sweet syndrome (SS) has been described and termed histiocytoid SS (HSS). Clinically, patients had a typical SS, but on skin biopsy, the infiltrates were composed of immature nonblast myeloid cells. Nearly 50% of patients with HSS have myelodysplastic syndrome (MDS). HSS may be the first manifestation leading to the diagnosis of MDS. In 2015, a new category of myeloid dermatosis has been proposed, called myelodysplasia cutis, describing the specific skin infiltration by myelodysplastic cells in patients with MDS.
摘要:
2005年,已经描述了Sweet综合征(SS)的一种新的组织学变体,并将其称为组织细胞样SS(HSS)。临床上,患者有典型的SS,但皮肤活检,浸润由未成熟的非原始骨髓细胞组成。近50%的HSS患者患有骨髓增生异常综合征(MDS)。HSS可能是导致MDS诊断的第一表现。2015年,一种新的骨髓性皮肤病被提出,叫做骨髓发育不良,描述MDS患者骨髓增生异常细胞的特定皮肤浸润。
公众号