Abstract：
Migraine is a chronic neurological disorder that involves the brain, characterized by a series of abnormal neuronal networks interacting at different levels of the central and peripheral nervous system. Furthermore, it is known that psychosocial features contribute to the exacerbation and chronicity of symptoms.
To compare the somatosensory and psychosocial profiles of migraine patients with a control group.
We conducted a cross-sectional study comparing the somatosensory and psychosocial profiles of patients with migraine and healthy volunteers. A total of 52 women were included. For the somatosensory profile, Mechanical Detection Threshold (MDT), Pressure Pain Threshold (PPT), Temporal Summation (TS), and Conditioned Pain Modulation (CPM) in the trigeminal and extra-trigeminal areas were evaluated. Psychosocial profiles were assessed using questionnaires, the Central Sensitization Inventory, the Generalized Anxiety Disorders, the Pain Catastrophizing Scale, and the Tampa Scale of Kinesiophobia. Mann-Whitney U test was used to compare differences in the profiles between groups. The significance level was set at 5%.
Migraine patients showed a loss of somatosensory function in the trigeminal area for MDT (p = 0.019, r = 0.34 and p = 0.011, r = 0.37 for the ophthalmic nerve and masseter muscle respectively), lower PPT in trigeminal and extra-trigeminal areas (p < 0.001, r=>0.60) and less efficient CPM (p < 0.001, r=>0.60). No statistically significant differences were found in the TS (p=>0.05). Statistically significant differences were found in all psychosocial variables (p = <0.001 r=>0.60).
Migraine patients showed loss of somatosensory function, lower pressure pain threshold, and an inhibitory pro-nociceptive profile with high scores on central sensitization and fear of movement compared to the control group.
To compare the somatosensory and psychosocial profiles of migraine patients with a control group.
We conducted a cross-sectional study comparing the somatosensory and psychosocial profiles of patients with migraine and healthy volunteers. A total of 52 women were included. For the somatosensory profile, Mechanical Detection Threshold (MDT), Pressure Pain Threshold (PPT), Temporal Summation (TS), and Conditioned Pain Modulation (CPM) in the trigeminal and extra-trigeminal areas were evaluated. Psychosocial profiles were assessed using questionnaires, the Central Sensitization Inventory, the Generalized Anxiety Disorders, the Pain Catastrophizing Scale, and the Tampa Scale of Kinesiophobia. Mann-Whitney U test was used to compare differences in the profiles between groups. The significance level was set at 5%.
Migraine patients showed a loss of somatosensory function in the trigeminal area for MDT (p = 0.019, r = 0.34 and p = 0.011, r = 0.37 for the ophthalmic nerve and masseter muscle respectively), lower PPT in trigeminal and extra-trigeminal areas (p < 0.001, r=>0.60) and less efficient CPM (p < 0.001, r=>0.60). No statistically significant differences were found in the TS (p=>0.05). Statistically significant differences were found in all psychosocial variables (p = <0.001 r=>0.60).
Migraine patients showed loss of somatosensory function, lower pressure pain threshold, and an inhibitory pro-nociceptive profile with high scores on central sensitization and fear of movement compared to the control group.
摘要：
背景：偏头痛是一种涉及大脑的慢性神经系统疾病，其特征是一系列异常的神经元网络在中枢和外周神经系统的不同层面相互作用。此外，众所周知，心理社会特征有助于症状的恶化和慢性化。
目的：比较偏头痛患者与对照组的体感和心理社会特征。
方法：我们进行了一项横断面研究，比较了偏头痛患者和健康志愿者的体感和心理社会特征。共有52名妇女参加。对于体感轮廓，机械检测阈值(MDT),压力疼痛阈值（PPT），时间求和(TS)，评估了三叉神经和三叉神经外区域的条件性疼痛调节（CPM）。使用问卷评估心理社会概况，中央敏化库存，广泛性焦虑症，疼痛灾难量表，和运动恐惧症的坦帕量表。使用Mann-WhitneyU检验比较各组之间的差异。显著性水平设定为5%。
结果：偏头痛患者因MDT而表现出三叉神经区的体感功能丧失（眼神经和咬肌分别为p=0.019，r=0.34和p=0.011，r=0.37），三叉神经和三叉神经外区域的PPT较低（p<0.001，r=>0.60），CPM效率较低（p<0.001，r=>0.60）。在TS中没有发现统计学上的显著差异(p=>0.05)。在所有心理社会变量中发现了统计学上的显着差异（p=<0.001r=>0.60）。
结论：偏头痛患者显示体感功能丧失，较低的压力疼痛阈值，与对照组相比，在中枢致敏和运动恐惧方面得分较高的抑制性伤害性感受谱。
目的：比较偏头痛患者与对照组的体感和心理社会特征。
方法：我们进行了一项横断面研究，比较了偏头痛患者和健康志愿者的体感和心理社会特征。共有52名妇女参加。对于体感轮廓，机械检测阈值(MDT),压力疼痛阈值（PPT），时间求和(TS)，评估了三叉神经和三叉神经外区域的条件性疼痛调节（CPM）。使用问卷评估心理社会概况，中央敏化库存，广泛性焦虑症，疼痛灾难量表，和运动恐惧症的坦帕量表。使用Mann-WhitneyU检验比较各组之间的差异。显著性水平设定为5%。
结果：偏头痛患者因MDT而表现出三叉神经区的体感功能丧失（眼神经和咬肌分别为p=0.019，r=0.34和p=0.011，r=0.37），三叉神经和三叉神经外区域的PPT较低（p<0.001，r=>0.60），CPM效率较低（p<0.001，r=>0.60）。在TS中没有发现统计学上的显著差异(p=>0.05)。在所有心理社会变量中发现了统计学上的显着差异（p=<0.001r=>0.60）。
结论：偏头痛患者显示体感功能丧失，较低的压力疼痛阈值，与对照组相比，在中枢致敏和运动恐惧方面得分较高的抑制性伤害性感受谱。
