关键词: Trichophyton indotineae over-the-counter drug steroid rosacea tinea faciei

Mesh : Humans Female Japan Nonprescription Drugs / therapeutic use Antifungal Agents / pharmacology Tinea / diagnosis drug therapy microbiology Trichophyton Rosacea / drug therapy Steroids / therapeutic use Erythema / drug therapy

来  源:   DOI:10.3314/mmj.23-00014

Abstract:
A Filipino woman in her forties had facial erythema that was being self-treated with over-the-counter (OTC) drugs purchased outside of Japan. The drugs included clobetasol propionate, antibiotic, and antifungal components. Her facial erythema symptoms were worse during summertime. KOH direct examination of annular erythema was positive for fungal hyphae and negative for Demodex folliculorum. Fungal culture revealed Trichophyton indotineae based on internal transcribed spacer sequence analysis. Minimal inhibitory concentration for terbinafine was 0.06 µg/mL. We made a diagnosis of tinea faciei with steroid rosacea. We treated the patient with oral itraconazole. Physicians should be aware of increasing T. indotineae infections and increasing self-medication using topical OTC steroids combined with antifungals and antibiotics not only in India but also among foreign people living in other countries such as Japan.
摘要:
一名四十多岁的菲律宾妇女面部红斑正在使用在日本以外购买的非处方药(OTC)进行自我治疗。这些药物包括丙酸氯倍他索,抗生素,和抗真菌成分。她的面部红斑症状在夏季更为严重。KOH直接检查环状红斑的真菌菌丝阳性,毛囊蠕形螨阴性。真菌培养根据内部转录间隔序列分析揭示了吲哚毛癣菌。特比萘芬的最低抑制浓度为0.06μg/mL。我们诊断为面部癣伴类固醇酒渣鼻。我们用口服伊曲康唑治疗患者。医生应该意识到,不仅在印度,而且在居住在日本等其他国家的外国人中,使用局部OTC类固醇与抗真菌药和抗生素联合使用,增加了吲哚虫感染和自我药疗。
公众号