Revised whole genome and DNA methylome of Mycobacterium marinum type strain ATCC 927T.

修订了 marinum 分枝杆菌型菌株 ATCC 927T 的全基因组和 DNA 甲基化组。

• 发表时间: 2024 Apr 11
• 来源期刊: Microbiol Resour Announc
• DOI: 10.1128/mra.01016-23
• PMID: 38415640
• 文章类型: Journal Article
• 作者列表: Savijoki K,Deptula P,Roberts RJ,Hammarén M,Yli-Kauhaluoma J,Varmanen P,Parikka M

关键词: DNA methylome; Mycobacterium marinum; SMRT-PacBio; genome analysis; plasmid; tuberculosis

Abstract

Mycobacterium marinum, a slow-growing Actinobacterium, typically induces tuberculosis-like disease in fish. Here, we report a new reference sequence for M. marinum ATCC 927T, along with its DNA methylome. This aims to maximize the research potential of this type strain and facilitates investigations into the pathomechanisms of human tuberculosis.

摘要

marinum分枝杆菌,生长缓慢的放线菌,通常会在鱼类中诱发结核病样疾病。这里,我们报告了一个新的参考序列，以及它的DNA甲基化。这旨在最大限度地提高这种类型菌株的研究潜力，并促进对人类结核病发病机制的研究。