PDF(Pubmed)
Abstract：
BACKGROUND: In this case series, a perioperative anticoagulation protocol for microvascular head and neck surgery in patients with thrombophilia is presented. Microvascular free-flap surgery is a standard procedure in head and neck surgery with high success rates. Nevertheless, flap loss-which is most often caused by thrombosis-can occur and has far-reaching consequences, such as functional impairment, prolonged hospitalization, and increased costs. The risk of flap loss owing to thrombosis is significantly increased in patients with thrombophilia. Therefore, perioperative anticoagulation is mandatory. To date, no perioperative anticoagulation protocol exists for these high-risk patients.
METHODS: We present three exemplary male Caucasian patients aged 53-57 years with free flap loss owing to an underlying, hidden thrombophilia.
CONCLUSIONS: We present a modified anticoagulation protocol for microvascular surgery in these high-risk patients, enabling successful microsurgical reconstruction.
METHODS: We present three exemplary male Caucasian patients aged 53-57 years with free flap loss owing to an underlying, hidden thrombophilia.
CONCLUSIONS: We present a modified anticoagulation protocol for microvascular surgery in these high-risk patients, enabling successful microsurgical reconstruction.
摘要：
背景：在本例系列中，介绍了血栓形成倾向患者微血管头颈部手术的围手术期抗凝方案。微血管游离皮瓣手术是头颈部手术的标准手术，成功率很高。然而，皮瓣丢失-最常见的是血栓形成-可以发生并具有深远的后果，如功能损害，住院时间延长,和增加的成本。血栓形成患者由于血栓形成而导致的皮瓣丢失的风险显着增加。因此,围手术期抗凝是强制性的.迄今为止,这些高危患者没有围手术期抗凝方案.
方法：我们介绍了三名典型的男性白人患者，年龄在53-57岁之间，由于潜在的，隐藏的血栓倾向.
结论：我们提出了针对这些高危患者的微血管手术的改良抗凝方案，使成功的显微外科重建。
方法：我们介绍了三名典型的男性白人患者，年龄在53-57岁之间，由于潜在的，隐藏的血栓倾向.
结论：我们提出了针对这些高危患者的微血管手术的改良抗凝方案，使成功的显微外科重建。
