PDF(Pubmed)
Abstract：
UNASSIGNED: Talaromyces marneffei is prevalent in South Asia. Latent Talaromyces marneffei infection of travellers make the diagnosis difficult. There are similarities in clinical manifestations between Talaromyces marneffei infection and lymphoma. Brain abscess is a rare form of Talaromyces marneffei infection.
UNASSIGNED: We reported a very rare case of a 19-year-old man with HIV infection who suffered from a brain mass and lymphadenopathy. His blood culture, bone marrow culture and sputum culture all grew Talaromyces marneffei. One month after treatment with voriconazole, the symptoms improved except brain mass. Surgical incision of the brain mass showed a compact mass, and pathological analysis showed the coexisting Talaromyces marneffei abscess and lymphoma. The patient is currently in a stable condition after receiving antifungal therapy and chemotherapy.
UNASSIGNED: Based on a case report of a traveller who suffered from a brain mass of Talaromyces marneffei abscess and lymphoma after a visit to an endemic area, this review summarized the cases where there was confusion between lymphoma and the brain abscess of Talaromyces marneffei. Talaromyces marneffei infection can be found globally due to the increasing number of international travels. Talaromyces marneffei infection and lymphoma had similar characteristics which is easy to misdiagnose in clinic. Infection may also be accompanied by tumors, especially in patients infected with HIV. The manifestations and imaging of brain abscess of Talaromyces marneffei were not characteristic in different patients.
UNASSIGNED: We reported a very rare case of a 19-year-old man with HIV infection who suffered from a brain mass and lymphadenopathy. His blood culture, bone marrow culture and sputum culture all grew Talaromyces marneffei. One month after treatment with voriconazole, the symptoms improved except brain mass. Surgical incision of the brain mass showed a compact mass, and pathological analysis showed the coexisting Talaromyces marneffei abscess and lymphoma. The patient is currently in a stable condition after receiving antifungal therapy and chemotherapy.
UNASSIGNED: Based on a case report of a traveller who suffered from a brain mass of Talaromyces marneffei abscess and lymphoma after a visit to an endemic area, this review summarized the cases where there was confusion between lymphoma and the brain abscess of Talaromyces marneffei. Talaromyces marneffei infection can be found globally due to the increasing number of international travels. Talaromyces marneffei infection and lymphoma had similar characteristics which is easy to misdiagnose in clinic. Infection may also be accompanied by tumors, especially in patients infected with HIV. The manifestations and imaging of brain abscess of Talaromyces marneffei were not characteristic in different patients.
摘要：
■马尔尼菲塔拉菌在南亚很普遍。旅行者潜伏的马尔尼菲塔拉菌感染使诊断变得困难。马尔尼菲塔拉菌感染与淋巴瘤的临床表现相似。脑脓肿是马尔尼菲塔拉菌感染的一种罕见形式。
■我们报道了一个非常罕见的病例，一名19岁的HIV感染者患有脑部肿块和淋巴结肿大。他的血培养,骨髓培养和痰培养都生长了马尔尼菲塔拉酵母。伏立康唑治疗后一个月，症状改善，除了脑质量。脑肿块的手术切口显示为致密肿块，病理分析显示马尔尼菲塔拉菌脓肿和淋巴瘤并存。患者目前在接受抗真菌治疗和化疗后病情稳定。
根据一例旅行者的病例报告，该旅行者在访问流行区后患有马尔尼菲塔拉氏菌脓肿和淋巴瘤的脑肿块，这篇综述总结了淋巴瘤与马尔尼菲塔拉霉素脑脓肿混淆的病例。由于越来越多的国际旅行，可以在全球发现马尔尼菲塔拉菌感染。马尔尼菲塔拉菌感染与淋巴瘤具有相似的特征，临床上易误诊。感染也可能伴有肿瘤，尤其是感染艾滋病毒的患者。不同患者的马尔尼菲塔拉菌脑脓肿的表现和影像学表现无特征性。
■我们报道了一个非常罕见的病例，一名19岁的HIV感染者患有脑部肿块和淋巴结肿大。他的血培养,骨髓培养和痰培养都生长了马尔尼菲塔拉酵母。伏立康唑治疗后一个月，症状改善，除了脑质量。脑肿块的手术切口显示为致密肿块，病理分析显示马尔尼菲塔拉菌脓肿和淋巴瘤并存。患者目前在接受抗真菌治疗和化疗后病情稳定。
根据一例旅行者的病例报告，该旅行者在访问流行区后患有马尔尼菲塔拉氏菌脓肿和淋巴瘤的脑肿块，这篇综述总结了淋巴瘤与马尔尼菲塔拉霉素脑脓肿混淆的病例。由于越来越多的国际旅行，可以在全球发现马尔尼菲塔拉菌感染。马尔尼菲塔拉菌感染与淋巴瘤具有相似的特征，临床上易误诊。感染也可能伴有肿瘤，尤其是感染艾滋病毒的患者。不同患者的马尔尼菲塔拉菌脑脓肿的表现和影像学表现无特征性。
