关键词: Gestational choriocarcinoma Non-gestational choriocarcinoma Ovarian choriocarcinoma ultrasound Ovarian germ cell tumors

来  源:   DOI:10.1007/s40477-023-00868-3

Abstract:
Choriocarcinoma of the ovary is a rare, highly malignant tumor showing malignant trophoblastic cells and produces human chorionic gonadotropins. It can be classified as gestational and non-gestational choriocarcinoma. Non-gestational choriocarcinoma is extremely rare. Treatment is Methotrexate-based chemotherapy for the gestational type. This case study is a rare case of ovarian choriocarcinoma managed by surgical resection, followed by methotrexate-based chemotherapy, and aimed to evaluate the ultrasound characteristics of ovarian choriocarcinoma and how to arrive at the diagnosis. In cases with an elevated serum beta-human chorionic gonadotropin (beta hCG), the finding of a highly vascularized adnexal mass on ultrasound evaluation should be underlined as a clue for suspecting choriocarcinoma, particularly if the female was young with no marriage history or history of sexual intercourse and also to be highly considered in married females with history of repeated abortions, molar pregnancy or uterine choriocarcinoma.
摘要:
卵巢绒毛膜癌是一种罕见的,显示恶性滋养细胞并产生人绒毛膜促性腺激素的高度恶性肿瘤。它可以分为妊娠期和非妊娠期绒毛膜癌。非妊娠绒毛膜癌极为罕见。妊娠类型的治疗是基于甲氨蝶呤的化疗。该病例研究是通过手术切除治疗的罕见卵巢绒毛膜癌,其次是以甲氨蝶呤为基础的化疗,目的探讨卵巢绒毛膜癌的超声特征及诊断方法。在血清β-人绒毛膜促性腺激素(β-hCG)升高的情况下,在超声评估中发现高度血管化的附件肿块应被强调为怀疑绒毛膜癌的线索,特别是如果女性年轻,没有婚姻史或性交史,并且在有反复堕胎史的已婚女性中也被高度考虑,磨牙妊娠或子宫绒毛膜癌。
公众号