Abstract：
Cardiovascular diseases (CVDs) remain a global health challenge and are the leading cause of deaths worldwide. Proteomics has emerged as a valuable tool for unraveling the complex molecular mechanisms underlying CVDs, offering insights into biomarker discovery, drug targets, and personalized medicine. This review explores key breakthroughs in proteomic applications related to CVDs, mainly coronary artery disease (CAD), ischemic heart diseases such as myocardial infarction (MI), and cardiomyopathies. Notable findings include potential biomarkers, therapeutic targets, and insights into disease pathogenesis. The review highlights the importance of proteomics in advancing our understanding of CVDs and shaping future therapeutic approaches.
摘要：
心血管疾病（CVDs）仍然是全球健康挑战，是全球死亡的主要原因。蛋白质组学已经成为一种有价值的工具，用于揭示心血管疾病背后的复杂分子机制，提供对生物标志物发现的见解，药物靶标,个性化医疗。这篇综述探讨了与CVD相关的蛋白质组学应用的重大突破，主要是冠状动脉疾病（CAD），缺血性心脏病，如心肌梗死(MI)，和心肌病。值得注意的发现包括潜在的生物标志物，治疗目标，以及对疾病发病机理的见解。这篇综述强调了蛋白质组学在促进我们对CVD的理解和塑造未来治疗方法方面的重要性。
