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Abstract：
BACKGROUND: There are a variety of determinants that are key to functional disability of older adults. However, little is known regarding the relationship between cognitive frailty and disability among older people. The aims of this study were to examine the associations between cognitive frailty and its six components with instrumental activities of daily living (IADL) functioning in community-dwelling older adults.
METHODS: A total of 313 community-dwelling older adults (aged ≥ 65 years) were recruited from eight community centers in central China. Cognitive frailty was operationalized using the Mini-Mental State Examination for the evaluation of cognitive status and the Fried criteria for the evaluation of physical frailty. The outcome was functional disability assessed by the IADL scale. The association between cognitive frailty, as well as its components, and IADL limitations was identified by conducting binary logistic regression analysis.
RESULTS: The prevalence of cognitive frailty was 8.9% in this study. The results showed that cognitive frailty (OR = 22.86) and frailty without cognitive impairment (OR = 8.15) were associated with IADL limitations. Subdimensions of cognitive frailty, exhaustion, weakness, low physical activity and cognitive impairment components were independently associated with IADL limitations.
CONCLUSIONS: Cognitive frailty was associated with a higher prevalence of disability. Interventions for improving cognitive frailty should be developed to prevent IADL disability among community-dwelling older adults in China.
METHODS: A total of 313 community-dwelling older adults (aged ≥ 65 years) were recruited from eight community centers in central China. Cognitive frailty was operationalized using the Mini-Mental State Examination for the evaluation of cognitive status and the Fried criteria for the evaluation of physical frailty. The outcome was functional disability assessed by the IADL scale. The association between cognitive frailty, as well as its components, and IADL limitations was identified by conducting binary logistic regression analysis.
RESULTS: The prevalence of cognitive frailty was 8.9% in this study. The results showed that cognitive frailty (OR = 22.86) and frailty without cognitive impairment (OR = 8.15) were associated with IADL limitations. Subdimensions of cognitive frailty, exhaustion, weakness, low physical activity and cognitive impairment components were independently associated with IADL limitations.
CONCLUSIONS: Cognitive frailty was associated with a higher prevalence of disability. Interventions for improving cognitive frailty should be developed to prevent IADL disability among community-dwelling older adults in China.
摘要：
背景：有多种决定因素是老年人功能性残疾的关键。然而,关于老年人认知虚弱与残疾之间的关系知之甚少。这项研究的目的是研究认知脆弱及其六个组成部分与社区居住的老年人的日常生活工具活动（IADL）功能之间的关联。
方法：从中国中部的8个社区中心招募了313名社区居住的老年人（年龄≥65岁）。使用迷你精神状态检查法评估认知状态，并使用Fried标准评估身体虚弱。结果是通过IADL量表评估的功能性残疾。认知脆弱之间的关联，以及它的组成部分，和IADL限制通过进行二元逻辑回归分析确定。
结果：本研究中认知虚弱的患病率为8.9%。结果表明，认知虚弱（OR=22.86）和无认知障碍的虚弱（OR=8.15）与IADL限制有关。认知脆弱的子维度，疲惫,弱点,低体力活动和认知障碍成分与IADL限制独立相关.
结论：认知虚弱与更高的残疾患病率相关。应制定改善认知虚弱的干预措施，以预防中国社区老年人的IADL残疾。
方法：从中国中部的8个社区中心招募了313名社区居住的老年人（年龄≥65岁）。使用迷你精神状态检查法评估认知状态，并使用Fried标准评估身体虚弱。结果是通过IADL量表评估的功能性残疾。认知脆弱之间的关联，以及它的组成部分，和IADL限制通过进行二元逻辑回归分析确定。
结果：本研究中认知虚弱的患病率为8.9%。结果表明，认知虚弱（OR=22.86）和无认知障碍的虚弱（OR=8.15）与IADL限制有关。认知脆弱的子维度，疲惫,弱点,低体力活动和认知障碍成分与IADL限制独立相关.
结论：认知虚弱与更高的残疾患病率相关。应制定改善认知虚弱的干预措施，以预防中国社区老年人的IADL残疾。
