PDF(Pubmed)
Abstract：
The electrocardiogram (ECG) is a non-invasive diagnostic tool holding significant clinical importance in the diagnosis and risk stratification of cardiac disease. However, access to large-scale, population-based digital ECG data for research purposes remains limited and challenging. Consequently, we established the Danish Nationwide ECG Cohort to provide data from standard 12-lead digital ECGs in both pre- and in-hospital settings, which can be linked to comprehensive Danish nationwide administrative registers on health and social data with long-term follow-up. The Danish Nationwide ECG Cohort is an open real-world cohort including all patients with at least one digital pre- or in-hospital ECG in Denmark from January 01, 2000, to December 31, 2021. The cohort includes data on standardized and uniform ECG diagnostic statements and ECG measurements including global parameters as well as lead-specific measures of waveform amplitudes, durations, and intervals. Currently, the cohort comprises 2,485,987 unique patients with a median age at the first ECG of 57 years (25th-75th percentiles, 40-71 years; males, 48%), resulting in a total of 11,952,430 ECGs. In conclusion, the Danish Nationwide ECG Cohort represents a novel and extensive population-based digital ECG dataset for cardiovascular research, encompassing both pre- and in-hospital settings. The cohort contains ECG diagnostic statements and ECG measurements that can be linked to various nationwide health and social registers without loss to follow-up.
摘要：
心电图（ECG）是一种非侵入性诊断工具，在心脏病的诊断和风险分层中具有重要的临床意义。然而,进入大规模，用于研究目的的基于人群的数字ECG数据仍然有限且具有挑战性.因此,我们建立了丹麦全国ECG队列，以在住院前和住院环境中提供来自标准12导联数字ECG的数据，它可以与丹麦全国卫生和社会数据综合行政登记册联系起来，并进行长期随访。丹麦全国ECG队列是一个开放的现实世界队列，包括2000年1月1日至2021年12月31日在丹麦至少有一个数字住院前或住院心电图的所有患者。该队列包括有关标准化和统一的ECG诊断声明和ECG测量的数据，包括全局参数以及特定于导线的波形幅度测量，持续时间,和间隔。目前,该队列包括2,485,987名独特患者，在第一次心电图检查时年龄中位数为57岁(第25-75百分位数，40-71岁；男性，48%），共产生11,952,430个心电图。总之,丹麦全国ECG队列代表了一个新颖而广泛的基于人群的数字ECG数据集，用于心血管研究，包括住院前和住院期间。该队列包含ECG诊断声明和ECG测量，可以与各种全国性的健康和社会登记册相关联，而不会失去随访。
