关键词: mucositis oral cavity prevention treatment tumors

Mesh : Humans Stomatitis / etiology prevention & control Neoplasms / drug therapy radiotherapy Quality of Life Mucous Membrane

来  源:   DOI:10.25122/jml-2023-0060   PDF(Pubmed)

Abstract:
Today, both Ukraine and the world at large are faced with a significant number of oncological diseases with various localizations. The current state of diagnosis, prevention, early detection, and access to treatment leads to a substantial number of people in each country\'s healthcare system who require comprehensive cancer treatments. Modern medical and diagnosis protocols in oncology involve the usage of ionizing radiation and aggressive toxic chemotherapeutic agents which can significantly disrupt the physiology of the mucous membrane of the digestive tract during treatment, especially of the oral cavity. The most common complication of complex anticancer therapy is the development of various lesions of the oral cavity, including mucositis, which harms the patient\'s quality of life, limits the doses of chemotherapy and radiation therapy the patient can receive, and also negatively affects the effectiveness of complex therapy treatment. Acute oral mucositis is observed among almost 100% of treatment cases. This is a significant problem for clinical oncology as it may also reduce patient compliance with comprehensive anticancer treatment. The results indicate the presence of oral problems in 100% of patients receiving specialized antitumor chemotherapy and radiotherapy, as well as the presence of a high need for specialized dental treatment.
摘要:
今天,乌克兰和整个世界都面临着大量不同定位的肿瘤疾病。目前的诊断状态,预防,早期发现,和获得治疗导致大量的人在每个国家的医疗保健系统谁需要全面的癌症治疗。肿瘤学中的现代医学和诊断方案涉及使用电离辐射和侵袭性有毒化学治疗剂,这些治疗剂可以在治疗期间显着破坏消化道粘膜的生理学,尤其是口腔。复杂的抗癌治疗最常见的并发症是口腔各种病变的发展,包括粘膜炎,这损害了病人的生活质量,限制患者可以接受的化疗和放疗的剂量,也会对复杂疗法的有效性产生负面影响。在几乎100%的治疗病例中观察到急性口腔粘膜炎。这是临床肿瘤学的重要问题,因为它还可能降低患者对综合抗癌治疗的依从性。结果表明,100%接受专门的抗肿瘤化疗和放疗的患者存在口腔问题,以及对专业牙科治疗的高度需求。
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