PDF(Pubmed)
Abstract：
Despite the significant advancements in prostate-specific antigen (PSA) screening and the diverse array of available treatments, prostate cancer (PCa) still significantly contributes to cancer-related illness. The most prevalent sites for metastases are bones, distant lymph nodes, and abdominal organs. Nevertheless, metastasis to the renal and retroperitoneal regions originating from prostate cancer constitutes an exceptionally uncommon clinical occurrence. Metastatic PCa commonly presents with elevated serum PSA levels, a hallmark of its diagnostic profile. However, there are instances where patients exhibit atypical metastatic patterns or maintain normal PSA levels. In the case under consideration, the patient exhibited a periureteral tumor with an indeterminate primary origin, subsequently confirmed to be metastatic prostate cancer. This case underscores the importance of recognizing the varied and sometimes elusive presentations of metastatic PCa. Despite its rarity, the occurrence of renal and retroperitoneal metastasis emphasizes the need for vigilance and a comprehensive understanding of the diverse manifestations of advanced PCa for timely and accurate diagnosis, which is paramount in optimizing patient care and outcomes.
摘要：
尽管在前列腺特异性抗原（PSA）筛查和各种可用的治疗方法方面取得了重大进展，前列腺癌（PCa）仍然是癌症相关疾病的重要原因。最常见的转移部位是骨骼，远处淋巴结,和腹部器官。然而，由前列腺癌引起的肾脏和腹膜后区域的转移构成了异常罕见的临床发生率。转移性PCa通常表现为血清PSA水平升高，它的诊断特征.然而,在某些情况下,患者表现出非典型转移模式或维持正常PSA水平.在本案中,患者表现为原发性来源不确定的输尿管周围肿瘤，随后证实为转移性前列腺癌。此病例强调了认识到转移性PCa的各种且有时难以捉摸的表现的重要性。尽管它很罕见,肾和腹膜后转移的发生强调需要警惕和全面了解晚期PCa的各种表现，以便及时准确诊断，这对于优化患者护理和结果至关重要。
