PDF(Pubmed)
Abstract：
Cryptogenic organising pneumonia (COP) is a form of idiopathic diffuse interstitial lung disease (ILD) that develops in response to a variety of unknown irritants. An essential component of the development of organising pneumonia (OP) is damage to type II pneumocytes and the alveolar basement membrane. An autoimmune illness called systemic sclerosis (SSc) has a significant death rate from cardiopulmonary involvement such as pulmonary hypertension and ILD. Arthritis is an autoimmune disorder, in which the patients experience extra-articular symptoms such as ILD during the course of their disease, and COP frequently coexists with these conditions. It is exceedingly uncommon for OP to occur as the initial sign of arthritis, and its clinical characteristics are still unclear. Scleroderma and inflammatory polyarthritis related to COP are presented in this report.
摘要：
隐源性组织性肺炎（COP）是特发性弥漫性间质性肺病（ILD）的一种形式，可响应各种未知的刺激物而发展。组织性肺炎（OP）发展的重要组成部分是对II型肺细胞和肺泡基底膜的损害。一种称为系统性硬化症（SSc）的自身免疫性疾病因心肺受累而具有显着的死亡率，例如肺动脉高压和ILD。关节炎是一种自身免疫性疾病,患者在疾病过程中会出现关节外症状，如ILD，和COP经常与这些条件共存。它是非常罕见的OP发生作为关节炎的最初迹象，其临床特征尚不清楚。本报告介绍了与COP相关的硬皮病和炎性多关节炎。
