PDF(Pubmed)
Abstract：
UNASSIGNED: Sclerosing variant of adenoid cystic carcinoma (SACC) is a rare variant of adenoid cystic carcinoma (ACC) with only two cases in the literature. In this article, we report two cases of SACCs and attempt to explain the reason for sclerosis and its association with the disease outcome.
UNASSIGNED: The first patient is a 43-year-old Dravidian Indian female with a chief complaint of pain and swelling in the right posterior cheek region of four months\' duration. The second patient is an 8-year-old boy with a well-defined swelling in the left cheek region.
UNASSIGNED: Both these cases were diagnosed as sclerosing variants of ACC.
UNASSIGNED: The tumour was surgically excised for both patients.
UNASSIGNED: Both the patients had no signs of residual disease/recurrence.
UNASSIGNED: We opine that the dense sclerotic stroma may have a preventing role in tumour cell growth and progression.
UNASSIGNED: The first patient is a 43-year-old Dravidian Indian female with a chief complaint of pain and swelling in the right posterior cheek region of four months\' duration. The second patient is an 8-year-old boy with a well-defined swelling in the left cheek region.
UNASSIGNED: Both these cases were diagnosed as sclerosing variants of ACC.
UNASSIGNED: The tumour was surgically excised for both patients.
UNASSIGNED: Both the patients had no signs of residual disease/recurrence.
UNASSIGNED: We opine that the dense sclerotic stroma may have a preventing role in tumour cell growth and progression.
摘要：
■腺样囊性癌（SACC）的硬化性变体是腺样囊性癌（ACC）的罕见变体，文献中只有2例。在这篇文章中,我们报告了2例SACCs病例,并试图解释硬化的原因及其与疾病结局的关系.
第一位患者是一名43岁的德拉威德印度女性，主诉右后颊区域疼痛和肿胀，持续时间为四个月。第二名患者是一名8岁男孩，左颊区域有明确的肿胀。
■这两种情况均被诊断为ACC的硬化变体。
■两名患者的肿瘤均通过手术切除。
■两名患者都没有残留疾病/复发的迹象。
■我们认为致密的硬化基质可能在肿瘤细胞生长和进展中具有阻止作用。
第一位患者是一名43岁的德拉威德印度女性，主诉右后颊区域疼痛和肿胀，持续时间为四个月。第二名患者是一名8岁男孩，左颊区域有明确的肿胀。
■这两种情况均被诊断为ACC的硬化变体。
■两名患者的肿瘤均通过手术切除。
■两名患者都没有残留疾病/复发的迹象。
■我们认为致密的硬化基质可能在肿瘤细胞生长和进展中具有阻止作用。
