关键词: Impacted mandibular third molar lornoxicam pre-emptive analgesia

来  源:   DOI:10.4103/ams.ams_134_22   PDF(Pubmed)

Abstract:
UNASSIGNED: The most common complication following third molar surgery is pain. The purpose of the study is to determine the efficacy of lornoxicam as a preventive analgesic in patients undergoing surgical removal of impacted mandibular third molars.
UNASSIGNED: This study included 26 participants aged 18-28 years with bilateral symmetrical third molars. Group A, the control group, received lornoxicam 8 mg 1 h after surgery, whereas Group B, the study group, received lornoxicam 8 mg 1 h before surgery. All patients were evaluated for pain at the 1st, 2nd, 4th, 6th, 8th and 12th post-operative hours. The number of rescue analgesics taken within 24 h of the procedure, as well as the first occurrence of pain postoperatively, was recorded and analysed.
UNASSIGNED: Using the Mann-Whitney U-test and Friedman\'s analysis, the resulting data were statistically analysed. When Group B was compared to Group A, there was a significant difference in pain reduction levels in the immediate post-operative hours. When compared to Group A, Group B had a lower need for rescue analgesics within the first 24 h postoperatively.
UNASSIGNED: Following mandibular third molar surgery, pre-emptive use of lornoxicam is effective in reducing post-operative pain and reducing the need for rescue analgesic consumption.
摘要:
第三磨牙手术后最常见的并发症是疼痛。该研究的目的是确定氯诺昔康作为预防性镇痛药在接受下颌阻生第三磨牙手术切除的患者中的疗效。
这项研究包括26名年龄在18-28岁之间的双侧对称第三磨牙的参与者。A组,对照组,手术后1小时接受氯诺昔康8毫克,而B组,研究组,手术前1小时接受氯诺昔康8毫克。所有患者在1日进行疼痛评估,2nd,第四,6th,术后8小时和12小时。手术后24小时内服用的抢救镇痛药的数量,以及术后第一次出现疼痛,进行了记录和分析。
使用曼-惠特尼U检验和弗里德曼的分析,对所得数据进行统计分析。当B组与A组比较时,术后即刻的疼痛减轻水平存在显著差异.与A组相比,B组在术后24小时内对抢救镇痛药的需求较低。
下颌第三磨牙手术后,先发制人使用氯诺昔康可有效减轻术后疼痛,并减少抢救镇痛剂的消耗.
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