UNASSIGNED: This study included 26 participants aged 18-28 years with bilateral symmetrical third molars. Group A, the control group, received lornoxicam 8 mg 1 h after surgery, whereas Group B, the study group, received lornoxicam 8 mg 1 h before surgery. All patients were evaluated for pain at the 1st, 2nd, 4th, 6th, 8th and 12th post-operative hours. The number of rescue analgesics taken within 24 h of the procedure, as well as the first occurrence of pain postoperatively, was recorded and analysed.
UNASSIGNED: Using the Mann-Whitney U-test and Friedman\'s analysis, the resulting data were statistically analysed. When Group B was compared to Group A, there was a significant difference in pain reduction levels in the immediate post-operative hours. When compared to Group A, Group B had a lower need for rescue analgesics within the first 24 h postoperatively.
UNASSIGNED: Following mandibular third molar surgery, pre-emptive use of lornoxicam is effective in reducing post-operative pain and reducing the need for rescue analgesic consumption.
■这项研究包括26名年龄在18-28岁之间的双侧对称第三磨牙的参与者。A组,对照组,手术后1小时接受氯诺昔康8毫克,而B组,研究组,手术前1小时接受氯诺昔康8毫克。所有患者在1日进行疼痛评估,2nd,第四,6th,术后8小时和12小时。手术后24小时内服用的抢救镇痛药的数量,以及术后第一次出现疼痛,进行了记录和分析。
■使用曼-惠特尼U检验和弗里德曼的分析,对所得数据进行统计分析。当B组与A组比较时,术后即刻的疼痛减轻水平存在显著差异.与A组相比,B组在术后24小时内对抢救镇痛药的需求较低。
■下颌第三磨牙手术后,先发制人使用氯诺昔康可有效减轻术后疼痛,并减少抢救镇痛剂的消耗.