关键词: Abducens diplopía Carcinoma nasofaríngeo Diplopia Diplopía Diplopía abducens Nasopharyngeal carcinoma Neuromiotonía ocular Ocular neuromyotonia Radioterapia Radiotherapy

Mesh : Humans Female Middle Aged Nasopharyngeal Neoplasms / radiotherapy Isaacs Syndrome / etiology diagnosis Nasopharyngeal Carcinoma / radiotherapy Diplopia / etiology Carcinoma / radiotherapy Abducens Nerve Diseases / etiology Radiation Injuries / etiology complications Radiotherapy / adverse effects

来  源:   DOI:10.1016/j.oftale.2024.01.017

Abstract:
Ocular neuromyotonia (ONM) is an infrequent disorder characterised by recurrent episodes of binocular diplopia caused by paroxysmal contraction of one or several extraocular muscles innervated by the same cranial nerve. It can be triggered spontaneously or caused by prolonged contraction of specific eye muscle(s) and is usually related to a local intracranial radiotherapy antecedent. We report the case of a 46-year-old woman who developed intermittent episodes of binocular diplopia eight years after radiotherapy for a nasopharyngeal carcinoma. After a complete neuro-ophthalmic assessment we diagnosed the case as an abducens nerve neuromyotonia. Although it is infrequent, radiotherapy to the nasopharynx is a possible cause of ONM, due to the proximity to the base of the skull and extraocular motor nerve pathways, especially that of the VI cranial nerve, as is the case presented in this article, about a patient whose history is a nasopharyngeal carcinoma treated with local radiotherapy.
摘要:
眼部神经肌强直(ONM)是一种罕见的疾病,其特征是由同一颅神经支配的一个或多个眼外肌的阵发性收缩引起的双眼复视反复发作。它可以自发触发或由特定眼肌的长时间收缩引起,并且通常与局部颅内放疗前因有关。我们报道了一名46岁的女性,该女性在鼻咽癌放疗后八年出现间歇性双眼复视发作。经过完整的神经眼科评估,我们将该病例诊断为外展神经神经肌强直。虽然不常见,对鼻咽部的放射治疗是ONM的可能原因,由于靠近颅底和眼外运动神经通路,尤其是第六脑神经,正如本文所介绍的那样,关于一名患者的病史是鼻咽癌,接受了局部放射治疗。
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