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Abstract：
Background and Objectives: Legionnaires\' disease (LD) is an acute respiratory disease with increasing annual numbers of reported domestic and global cases. This study aimed to establish foundational data for the prevention and control of LD by investigating the occurrence and infection routes of reported and suspected cases of LD in Gyeonggi Province, Korea, from January 2016 to December 2022, and by and analyzing the risk factors for death. Materials and Methods: A sex-and-age standardization was performed on LD patients and suspected cases reported in Gyeonggi Province. The monthly average number of confirmed cases was visualized using graphs, and a survival analysis was performed using Kaplan-Meier survival curves. The mortality risk ratio was estimated using the Cox proportional hazards model. Results: The incidence of LD in Gyeonggi Province mirrored the national trend, peaking in July with the highest number of confirmed and suspected cases. While there was no significant difference in survival rates by age, the survival rate was higher for suspected cases when analyzed separately. Comparing the death ratio by infection route, nosocomial infections showed the highest death ratio, and intensive care unit (ICU) admission and the presence of coinfections were significantly correlated with mortality. Factors such as nosocomial infection, admission within 1 to 3 days following diagnosis, and the development of complications were factors contributing to a higher risk of death. Conclusions: The general characteristics of patients with LD were similar to those suggested by previous studies. The proportion of community-acquired infections was lower than in previous studies, but the length of hospital stay was similar for survivors and the deceased, and the mortality rate within 30 days after diagnosis was higher for nosocomial infections. In conclusion, nosocomial infection, a period of up to 3 days from admission to diagnosis, and complications were significantly related to the mortality rate of LD.
摘要：
背景和目的：军团病（LD）是一种急性呼吸道疾病，每年报告的国内和全球病例数都在增加。本研究旨在通过调查京坪省报告和疑似病例的发生和感染途径，为预防和控制LD建立基础数据。韩国,从2016年1月至2022年12月，并通过分析死亡的危险因素。材料和方法：对京坪省报告的LD患者和疑似病例进行性别和年龄标准化。每月平均确诊病例数用图表显示,使用Kaplan-Meier生存曲线进行生存分析.使用Cox比例风险模型估计死亡风险比。结果:京坪省LD的发病率反映了全国趋势,7月达到峰值，确诊和疑似病例数量最高。虽然不同年龄的生存率没有显着差异，单独分析时,疑似病例的生存率较高.按感染途径比较死亡率，医院感染的死亡率最高，重症监护病房(ICU)的入住和合并感染的存在与死亡率显著相关.医院感染等因素，诊断后1至3天内入院，和并发症的发展是导致较高死亡风险的因素。结论：LD患者的一般特征与先前研究的相似。社区获得性感染的比例低于以前的研究，但是幸存者和死者的住院时间相似，医院感染诊断后30天内的死亡率较高。总之,医院感染,从入院到诊断长达3天，并发症与LD病死率显著相关。
