PDF(Pubmed)
Abstract：
(1) Background: Whole-body magnetic resonance imaging (WB-MRI) is central to defining total inflammatory burden in juveniles with arthritis. Our aim was to determine and compare the initial distribution of lesions in the WB-MRI in patients with chronic recurrent multifocal osteomyelitis (CRMO), juvenile idiopathic arthritis (JIA), their overlapping syndrome (OS), and with Non-specific Arthropathy (NA). (2) Methods: This retrospective single center study was performed on an Avanto 1.5-T MRI scanner with a dedicated multichannel surface coil system. A total of 173 pediatric patients were included with the following final diagnoses: CRMO (15.0%), JIA (29.5%), OS (4.6%), and NA (50.9%). (3) Results: Bone marrow edema (BME) was the most common abnormality, being seen in 100% patients with CRMO, 88% with OS, 55% with JIA, and 11% with NA. The bones of the lower extremities were the most affected in all compared entities. Effusion was seen in 62.5% children with OS, and in 52.9% with JIA, and in CRMO and NA, the exudate was sporadic. Enthesitis was found in 7.8% of patients with JIA and 3.8% with CRMO, and myositis was seen in 12.5% of patients with OS and in 3.9% with JIA. (4) Conclusions: The most frequent indication for WB-MRI in our center was JIA. The most common pathology in all rheumatic entities was BME, followed by effusion mainly seen in in OS and JIA. Enthesitis and myositis were less common; no case was observed in NA.
摘要：
（1）背景：全身磁共振成像（WB-MRI）对于定义患有关节炎的青少年的总炎症负担至关重要。我们的目的是确定和比较慢性复发性多灶性骨髓炎（CRMO）患者WB-MRI中病变的初始分布。幼年特发性关节炎（JIA），它们的重叠综合征(OS)，和非特异性关节病（NA）。（2）方法：这项回顾性单中心研究是在带有专用多通道表面线圈系统的Avanto1.5-TMRI扫描仪上进行的。共有173名儿科患者被纳入以下最终诊断：CRMO（15.0％），JIA（29.5%），OS（4.6%），和NA（50.9%）。(3)结果:骨髓水肿是最常见的异常,在100%的CRMO患者中看到，88%的操作系统，55%与JIA，和11％与NA。在所有比较的实体中，下肢的骨骼受影响最大。62.5%OS患儿出现积液,在JIA的52.9%中，在CRMO和NA，渗出物是零星的。JIA和CRMO的患者分别占7.8％和3.8％，12.5%的OS患者和3.9%的JIA患者出现肌炎。（4）结论：本中心最常见的WB-MRI指征是JIA。所有风湿性实体中最常见的病理是BME，其次是积液，主要见于OS和JIA。端炎和肌炎较少见；在NA中未观察到病例。
