PDF(Pubmed)
Abstract：
The muscle-tendon junction (MTJ) is a highly specific tissue interface where the muscle\'s fascia intersects with the extracellular matrix of the tendon. The MTJ functions as the particular structure facilitating the transmission of force from contractive muscle fibers to the skeletal system, enabling movement. Considering that the MTJ is continuously exposed to constant mechanical forces during physical activity, it is susceptible to injuries. Ruptures at the MTJ often accompany damage to both tendon and muscle tissues. In this review, we attempt to provide a precise definition of the MTJ, describe its subtle structure in detail, and introduce therapeutic approaches related to MTJ tissue engineering. We hope that our detailed illustration of the MTJ and summary of the representative research achievements will help researchers gain a deeper understanding of the MTJ and inspire fresh insights and breakthroughs for future research.
摘要：
肌肉-肌腱接头（MTJ）是一种高度特异性的组织界面，肌肉筋膜与肌腱的细胞外基质相交。MTJ用作促进力从收缩肌纤维传递到骨骼系统的特定结构。启用运动。考虑到MTJ在身体活动期间连续暴露于恒定的机械力，容易受伤。MTJ的破裂通常伴随着肌腱和肌肉组织的损伤。在这次审查中,我们试图提供MTJ的精确定义，详细描述它微妙的结构，并介绍了与MTJ组织工程相关的治疗方法。我们希望我们对MTJ的详细说明和对代表性研究成果的总结将有助于研究人员对MTJ有更深入的了解，并为未来的研究带来新的见解和突破。
