关键词: HPA-axis Maslach Burnout Inventory TSST Trier Social Stress Test burnout cardiovascular health physicians serum cortisol stress reactivity

来  源:   DOI:10.3390/biomedicines12020335   PDF(Pubmed)

Abstract:
BACKGROUND: Physician burnout, characterized by chronic job-related stress leading to emotional exhaustion, depersonalization, and reduced personal accomplishment. This cross-sectional study investigates cortisol reactivity in male physicians with burnout compared to healthy controls during an acute psychosocial stress test.
METHODS: Sixty male physicians (30 burnout, 30 healthy controls) participated between September 2019 and December 2021 to investigate the impact of burnout on cardiovascular health. Salivary cortisol levels were measured before and after a Trier Social Stress Test (TSST). Burnout was assessed with the Maslach Burnout Inventory-Human Services Survey (MBI-HSS). Covariates included age, BMI, and physical activity. Data were analyzed using repeated measures analysis and area under the curve analysis.
RESULTS: Male physicians with burnout exhibited significantly greater cortisol reactivity during the TSST, notably post-stress to 15 min post-stress. Emotional exhaustion correlated with reduced cortisol increase from pre-stress and smaller post-stress to 15- and 45-min declines.
CONCLUSIONS: Findings suggest heightened cortisol reactivity in male physicians with burnout, possibly reflecting initial chronic stress stages. This study highlights the necessity for long-term research on cortisol\'s influence on cardiovascular health and stress responses across diverse groups.
CONCLUSIONS: The findings contribute to comprehending physiological responses in burnout-afflicted physicians, emphasizing cortisol reactivity\'s pivotal role in stress-related research and its potential health implications, particularly within the burnout context.
摘要:
背景:医生倦怠,其特点是长期与工作相关的压力导致情绪疲惫,去个性化,降低个人成就感。这项横断面研究调查了在急性心理社会压力测试中,与健康对照相比,职业倦怠的男性医生的皮质醇反应性。
方法:60名男性医生(30名职业倦怠,30名健康对照)在2019年9月至2021年12月期间参加了调查,以调查倦怠对心血管健康的影响。在Trier社会压力测试(TSST)之前和之后测量唾液皮质醇水平。倦怠是通过Maslach倦怠清单-人类服务调查(MBI-HSS)进行评估的。协变量包括年龄,BMI,和身体活动。使用重复测量分析和曲线下面积分析来分析数据。
结果:患有倦怠的男性医生在TSST期间表现出明显更大的皮质醇反应性,特别是应激后至应激后15分钟。情绪疲惫与皮质醇减少相关,从压力前和较小的压力后增加到15分钟和45分钟的下降。
结论:研究结果表明,职业倦怠的男性医生皮质醇反应性增强,可能反映了最初的慢性应激阶段。这项研究强调了长期研究皮质醇对不同群体心血管健康和应激反应的影响的必要性。
结论:这些发现有助于理解职业倦怠的医生的生理反应,强调皮质醇反应性在压力相关研究中的关键作用及其潜在的健康影响,特别是在倦怠的背景下。
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