PDF(Pubmed)
Abstract：
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in a zoological institution were initially reported in March 2020. Since then, at least 94 peer-reviewed cases have been reported in zoos worldwide. Among the affected animals, nonhuman primates, carnivores, and artiodactyls appear to be most susceptible to infection, with the Felidae family accounting for the largest number of reported cases. Clinical symptoms tend to be mild across taxa; although, certain species exhibit increased susceptibility to disease. A variety of diagnostic tools are available, allowing for initial diagnostics and for the monitoring of infectious risk. Whilst supportive therapy proves sufficient in most cases, monoclonal antibody therapy has emerged as a promising additional treatment option. Effective transmission of SARS-CoV-2 in some species raises concerns over potential spillover and the formation of reservoirs. The occurrence of SARS-CoV-2 in a variety of animal species may contribute to the emergence of variants of concern due to altered viral evolutionary constraints. Consequently, this review emphasizes the need for effective biosecurity measures and surveillance strategies to prevent and control SARS-CoV-2 infections in zoological institutions.
摘要：
严重急性呼吸道综合症冠状病毒2（SARS-CoV-2）感染最初于2020年3月报告。从那以后,全世界动物园至少报告了94例同行评审病例.在受影响的动物中，非人灵长类动物,食肉动物,偶蹄动物似乎最容易受到感染，Felidae家族报告的病例数量最多。不同分类群的临床症状往往较轻；尽管，某些物种对疾病的易感性增加。各种诊断工具可用，允许初步诊断和监测感染风险。虽然在大多数情况下支持治疗被证明是足够的，单克隆抗体疗法已成为一种有希望的额外治疗选择。SARS-CoV-2在某些物种中的有效传播引起了人们对潜在溢出和水库形成的担忧。由于病毒进化限制的改变，SARS-CoV-2在各种动物物种中的出现可能有助于引起关注的变体的出现。因此,本综述强调需要有效的生物安全措施和监测策略来预防和控制动物机构中的SARS-CoV-2感染.
