关键词: ERIraos early recognition prodromal symptoms risk for psychosis transition

来  源:   DOI:10.1111/eip.13519

Abstract:
OBJECTIVE: Validated assessment tools are needed to identify clinically high risk for psychosis. This study aimed to validate the early recognition inventory ERIraos, which consists of the ERIraos Checklist for risk screening and the ERIraos Symptom List for a more thorough risk assessment in the Estonian language to detect psychotic prodromal symptoms.
METHODS: A prospective cohort study provided an opportunity to evaluate the characteristics of the ERIraos instrument in predicting the increased risk of a psychotic disorder in the future. The 177 study participants, aged 13-42 years old, were divided into groups without an increased risk and three risk groups with different risk severity levels based on the ERIraos Symptom List assessment.
RESULTS: The results indicated excellent inter-rater reliability for the ERIraos Symptom List total score. The ability of the ERIraos checklist to screen persons with an elevated psychosis risk was very good (ROC-AUC = 0.86). The capability of the ERIraos Symptom List scores to predict the probability of transitioning to psychosis within 2 years was very good (ROC-AUC = 0.83). Brief limited intermittent psychotic symptoms and observable behavioural and affective symptoms were statistically significant predictors of transition to psychosis. There were strong and statistically significant correlations between the ERIraos Symptom List scores and other clinical measures assessing functioning and psychopathology.
CONCLUSIONS: The results of this study demonstrate the reliability and validity of the Estonian version of the ERIraos instrument and support the usability of ERIraos as a two-step tool for the early recognition of psychosis risk.
摘要:
目的:需要经过验证的评估工具来确定精神病的临床高风险。本研究旨在验证早期识别清单ERIraos,其中包括用于风险筛查的ERIraos清单和用于以爱沙尼亚语进行更彻底的风险评估的ERIraos症状清单,以检测精神病性前驱症状。
方法:一项前瞻性队列研究提供了一个机会来评估ERIraos工具在预测未来精神病风险增加方面的特征。177名研究参与者,13-42岁,根据ERIras症状列表评估,将其分为风险不增加的组和风险严重程度不同的三个风险组。
结果:结果表明,ERIraos症状列表总分的评分者间可靠性很好。ERIraos检查表筛选精神病风险升高者的能力非常好(ROC-AUC=0.86)。ERIras症状列表评分预测2年内转变为精神病的概率的能力非常好(ROC-AUC=0.83)。短暂的间歇性精神病症状以及可观察到的行为和情感症状是向精神病过渡的统计学显着预测因素。ERIras症状列表评分与其他评估功能和精神病理学的临床指标之间存在强烈且统计学上显着的相关性。
结论:这项研究的结果证明了爱沙尼亚版本的ERIraos工具的可靠性和有效性,并支持ERIraos作为早期识别精神病风险的两步工具的可用性。
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