PDF(Pubmed)
Abstract：
BACKGROUND: X-linked hypophosphatemia (XLH) is a type of vitamin D-resistant rickets. It is the most common form of it and is related with oral health problems. This study aimed to analyze the OHRQoL of people suffering from XLH and measure physical oral health to confirm or refute evidence of reduced oral health.
METHODS: The German version of the Oral Health Impact Profile (OHIP-14G), was used to measure OHRQoL. All study participants underwent clinical examination, and oral health was scored using the Physical Oral Health Index (PhOX).
RESULTS: A total of 26 people participated in the study, of whom five were male and 21 were female. The average participant age was 40.9 ± 12.8 years. The OHIP-14G score was 14.3 (± 12.1; 95% CI: 9.37. 19.16) points (range 0-44 points). The PhOX score was 77.1 (± 9.9; 95% CI: 73.10-81.13) points (range 61-95 points).
CONCLUSIONS: The results of this study confirm that oral health and OHRQoL are both reduced in the studied cohort of people affected by XLH. Particular attention should be paid to perfect oral hygiene in people with XLH, as the impaired enamel mineralisation increases the risk of caries and thus also the occurrence of apical infections.
METHODS: The German version of the Oral Health Impact Profile (OHIP-14G), was used to measure OHRQoL. All study participants underwent clinical examination, and oral health was scored using the Physical Oral Health Index (PhOX).
RESULTS: A total of 26 people participated in the study, of whom five were male and 21 were female. The average participant age was 40.9 ± 12.8 years. The OHIP-14G score was 14.3 (± 12.1; 95% CI: 9.37. 19.16) points (range 0-44 points). The PhOX score was 77.1 (± 9.9; 95% CI: 73.10-81.13) points (range 61-95 points).
CONCLUSIONS: The results of this study confirm that oral health and OHRQoL are both reduced in the studied cohort of people affected by XLH. Particular attention should be paid to perfect oral hygiene in people with XLH, as the impaired enamel mineralisation increases the risk of caries and thus also the occurrence of apical infections.
摘要：
背景：X-连锁低磷酸盐血症（XLH）是一种维生素D抗性病。它是最常见的形式，与口腔健康问题有关。这项研究旨在分析患有XLH的人的OHRQoL，并测量身体口腔健康，以确认或反驳口腔健康减少的证据。
方法：德文版口腔健康影响简介（OHIP-14G），用于测量OHRQoL。所有研究参与者都接受了临床检查，口腔健康使用身体口腔健康指数（PhOX）进行评分。
结果：共有26人参与了这项研究，其中5人是男性，21人是女性。参与者平均年龄为40.9±12.8岁。OHIP-14G评分为14.3(±12.1;95%CI:9.37。19.16）分（范围0-44分）。PhOX评分为77.1(±9.9;95%CI:73.10-81.13)分(范围61-95分)。
结论：这项研究的结果证实，在受XLH影响的研究人群中，口腔健康和OHRQoL均降低。应特别注意XLH患者的口腔卫生，由于受损的釉质矿化会增加龋齿的风险，因此也会增加根尖感染的发生。
方法：德文版口腔健康影响简介（OHIP-14G），用于测量OHRQoL。所有研究参与者都接受了临床检查，口腔健康使用身体口腔健康指数（PhOX）进行评分。
结果：共有26人参与了这项研究，其中5人是男性，21人是女性。参与者平均年龄为40.9±12.8岁。OHIP-14G评分为14.3(±12.1;95%CI:9.37。19.16）分（范围0-44分）。PhOX评分为77.1(±9.9;95%CI:73.10-81.13)分(范围61-95分)。
结论：这项研究的结果证实，在受XLH影响的研究人群中，口腔健康和OHRQoL均降低。应特别注意XLH患者的口腔卫生，由于受损的釉质矿化会增加龋齿的风险，因此也会增加根尖感染的发生。
