关键词: Traditional Chinese Medicine acupuncture leg ulcers sickle-cell disease

来  源:   DOI:10.1089/acu.2023.0046   PDF(Pubmed)

Abstract:
UNASSIGNED: Sickle-cell diseases (SCD) are a group of hereditary disorders in which a specific mutation in the gene that encodes the hemoglobin ß chain leads to formation of an anomalous hemoglobin molecule (HbS) with high polymerization power. This leads to sickling of erythrocytes in situations of low oxygen tension, such as in microcirculation, resulting in peripheral microvasculature occlusion, chronic hemolysis, inflammation, and damage to several target organs. Malleolar ulcers are among the most-debilitating complications of the disease, as they are associated with significant pain, secondary infections, and social impact due to their aesthetic impairment. There are no completely satisfactory therapeutic options for this complication; local healing agents, antibiotics, and dressings are used, with high rates of recurrence and complications, such as osteomyelitis and even limb amputation.
UNASSIGNED: This case study evaluated the effect of Traditional Chinese Medicine techniques on chronic malleolar ulcers in a 49-year-old male patient. Ten sessions of systemic acupuncture (combinations involving Source, Master, Energetic Action, and Extraordinary Vessels points), auriculotherapy, and dressing with magnets were conducted.
UNASSIGNED: Although the primary outcome sought was not reached (decrease in ulcer diameters), this patient had great reduction of local pain, a decrease in limb edema, and important reduction of his inflammatory condition, reflected in his decreasing blood levels of C-reactive protein.
UNASSIGNED: These results show that acupuncture should be considered as an important auxiliary treatment for SCD complications.
摘要:
镰状细胞病(SCD)是一组遗传性疾病,其中编码血红蛋白β链的基因中的特定突变导致形成具有高聚合能力的异常血红蛋白分子(HbS)。这导致在低氧张力的情况下红细胞的镰状化,比如在微循环中,导致外周微血管阻塞,慢性溶血,炎症,以及对几个靶器官的损伤。踝溃疡是该疾病最令人衰弱的并发症之一,因为它们与严重的疼痛有关,继发感染,和社会影响,由于他们的审美障碍。对于这种并发症,没有完全令人满意的治疗选择;局部愈合剂,抗生素,使用敷料,高复发率和并发症,如骨髓炎,甚至截肢。
该案例研究评估了中医技术对一名49岁男性患者慢性踝溃疡的影响。十次全身针灸(涉及来源的组合,主人,精力充沛的行动,和非凡的船只点),耳穴疗法,并用磁铁进行敷料。
尽管未达到所寻求的主要结果(溃疡直径减小),这个病人的局部疼痛减轻了很多,肢体水肿减少,减轻他的炎症,反映在他的血C反应蛋白水平下降。
这些结果表明,针灸应被视为SCD并发症的重要辅助治疗方法。
公众号