METHODS: This prospective study included 30 patients diagnosed with NLDO who underwent external DCR surgery. Tear meniscus (TM) parameters, including height, depth and area, were measured using anterior segment optical coherence tomography. Lacrimal symptom questionnaire (LacQ), Munk scores and Glasgow benefit inventories (GBI) were collected. Statistical analysis was performed to evaluate the correlation between tear meniscus changes and improvements in QoL.
RESULTS: TM height, depth and area decreased from preoperative median measurements (0.09 mm2, 0.37 mm, 0.56 mm) to postoperative median measurements (0.03 mm2, 0.21 mm, 0.30 mm) (p < 0.001). Lacrimal symptom scores and Munk scores showed a significant improvement at 3-month postoperatively (p < 0.001). The GBI scores also demonstrated a significant improvement, indicating a positive impact on the patients\' QoL. (p < 0.001). A statistically significant correlation was found between the change in TM parameters and LacQ lacrimal symptom scores.
CONCLUSIONS: External DCR surgery leads to significant improvements in tear meniscus parameters and quality of life outcomes in patients with NLDO. The decreased in TM height and TM area indicates improved tear film dynamics and decreased tear volume, which positively impact the patients\' ocular comfort and overall well-being. This study highlights the importance of tear meniscus evaluation as a potential market for assessing the success of DCR surgery and its impact on patients\' QoL.
方法:这项前瞻性研究包括30例诊断为NLDO的患者,这些患者接受了外部DCR手术。撕裂弯月面(TM)参数,包括高度,深度和面积,使用眼前段光学相干断层扫描进行测量。泪腺症状问卷(LacQ),收集了Munk评分和格拉斯哥福利清单(GBI)。进行统计分析以评估泪液半月板变化与QoL改善之间的相关性。
结果:TM高度,深度和面积从术前中值测量值(0.09mm2,0.37mm,0.56mm)至术后中位数测量值(0.03mm2,0.21mm,0.30mm)(p<0.001)。泪腺症状评分和Munk评分在术后3个月显示显著改善(p<0.001)。GBI评分也显示出显著改善,表明对患者QoL的积极影响。(p<0.001)。TM参数的变化与LacQ泪腺症状评分之间存在统计学上的显着相关性。
结论:外部DCR手术可显著改善NLDO患者的泪液半月板参数和生活质量。TM高度和TM面积的减少表明泪膜动力学改善和泪液体积减少。这对患者的眼部舒适度和整体健康有积极影响。这项研究强调了泪液半月板评估作为评估DCR手术成功及其对患者QoL影响的潜在市场的重要性。