PDF(Pubmed)
Abstract：
Toxoplasma gondii and Trichinella spp. are critical tissue-dwelling foodborne zoonotic parasites associated with pork consumption and pig rearing. Despite being a major pig-rearing region in the country, Northeastern India has not undergone any investigation regarding the presence of T. gondii and Trichinella spp. in pigs. Therefore, this study aims to determine the seroprevalence of T. gondii and Trichinella spp. and identify associated risk factors in pigs reared by tribal communities and small-holder livestock farmers in the northeastern region of India. In a cross-sectional serological survey, 400 pigs from 400 households across five northeastern states of India underwent testing for the seroprevalence of porcine toxoplasmosis and trichinellosis. Serum samples (80 from each state) were analyzed using commercially available ELISA assays. Data on backyard farm characteristics and various management aspects were collected, and risk factors linked with prevalence were analyzed through univariate and multivariate logistic regression analysis. The findings revealed that the apparent and true prevalence of anti-T. gondii antibodies were 45% (40.12-49.88, 95% CI) and 45.7% (40.7-50.69, 95% CI), respectively. As for anti- Trichinella antibodies, both the apparent and true prevalence were 0.75% (-0.1-1.6, 95% CI). The univariate and multivariate analyses indicated that age above 24 months (OR 7.20, 95% CI 2.45-23.71), exposure to cats (OR = 5.87, 95% CI 2.55-14.05), and farms operating for breeding purposes (OR = 5.60, 95% CI 3.01-11.04) were significant risk factors associated with the seroprevalence of T. gondii. This study marks the initial documentation of the seroprevalence of T. gondii and Trichinella spp. in pigs reared by tribal communities in Northeastern India. The results emphasize the significance of these parasites as foodborne zoonotic threats in the region, potentially posing substantial public health risks, especially within tribal and rural communities. The insights derived from this research could be valuable in formulating targeted preventive and control strategies against T. gondii and Trichinella spp. in pigs, not only in this region but also in areas with similar rearing practices.
摘要：
弓形虫和旋毛虫。是与猪肉消费和猪饲养相关的关键的组织居住食源性人畜共患病寄生虫。尽管是该国主要的养猪地区，印度东北部尚未对弓形虫和旋毛虫的存在进行任何调查。在猪因此,本研究旨在确定弓形虫和旋毛虫的血清阳性率。并确定印度东北地区部落社区和小牲畜养殖者饲养的猪的相关风险因素。在横断面血清学调查中，来自印度东北五个州的400户家庭的400头猪接受了猪弓形虫病和旋毛虫病的血清阳性率测试。使用可商购的ELISA测定法分析血清样品(来自每个州的80个)。收集了有关后院农场特征和各种管理方面的数据，通过单因素和多因素logistic回归分析与患病率相关的危险因素.研究结果表明，抗T.gondii抗体为45％（40.12-49.88，95％CI）和45.7％（40.7-50.69，95％CI），分别。至于抗旋毛虫抗体，表观患病率和真实患病率均为0.75%(-0.1~1.6,95%CI).单因素和多因素分析表明年龄大于24个月（OR7.20，95％CI2.45-23.71），暴露于猫（OR=5.87，95%CI2.55-14.05），和以育种为目的经营的农场（OR=5.60，95％CI3.01-11.04）是与弓形虫血清阳性率相关的重要危险因素。这项研究标志着弓形虫和旋毛虫的血清阳性率的初步文献。在印度东北部部落社区饲养的猪中。结果强调了这些寄生虫作为该地区食源性人畜共患病威胁的重要性，潜在的公共健康风险，特别是在部落和农村社区。从这项研究中得出的见解对于制定针对弓形虫和旋毛虫的有针对性的预防和控制策略可能是有价值的。在猪身上,不仅在这个地区，而且在有类似饲养做法的地区。
