Abstract：
BACKGROUND: The main aim of periodontal therapy is to halt the progression of periodontitis. Curcumin, one of the main components of Curcumin longa, has been well known to possess antimicrobial, anti-inflammatory, and even anticarcinogenic properties. This systematic review assessed the impact of local application of curcumin in the pocket on the clinical and microbiologic parameters as an adjunct to scaling and root planing in periodontitis patients.
METHODS: The electronic literature search retrieved 61 studies from PubMed, MEDLINE, and ScienceDirect. After screening titles, abstracts, and keywords and reading through these articles, we identified 9 articles meeting all inclusion criteria, which were included for systematic review.
RESULTS: There was a significant difference in both clinical parameters in a short duration of a month after curcumin chips were placed as an adjunct to scaling and root planing as compared to the control. Local application of curcumin also results in slight to significant reduction in the red complex microorganisms.
CONCLUSIONS: This review suggested that local application of curcumin can be considered as a viable adjunct to mechanical debridement in periodontitis. However, further studies need to be conducted to establish its optimum dose, delivery method, and frequency in achieving the best clinical outcomes.
METHODS: The electronic literature search retrieved 61 studies from PubMed, MEDLINE, and ScienceDirect. After screening titles, abstracts, and keywords and reading through these articles, we identified 9 articles meeting all inclusion criteria, which were included for systematic review.
RESULTS: There was a significant difference in both clinical parameters in a short duration of a month after curcumin chips were placed as an adjunct to scaling and root planing as compared to the control. Local application of curcumin also results in slight to significant reduction in the red complex microorganisms.
CONCLUSIONS: This review suggested that local application of curcumin can be considered as a viable adjunct to mechanical debridement in periodontitis. However, further studies need to be conducted to establish its optimum dose, delivery method, and frequency in achieving the best clinical outcomes.
摘要：
背景：牙周治疗的主要目的是阻止牙周炎的进展。姜黄素,姜黄素的主要成分之一，众所周知，拥有抗菌药物，抗炎,甚至抗癌特性。这项系统评价评估了在牙周炎患者中局部应用姜黄素对临床和微生物参数的影响，作为牙垢和牙根平整的辅助手段。
方法：电子文献检索从PubMed，MEDLINE,和科学直接。筛选标题后，摘要,关键词和阅读这些文章，我们确定了9篇符合所有纳入标准的文章，包括在内进行系统审查。
结果：与对照组相比，在放置姜黄素片作为鳞屑和根部平整的辅助手段后的一个月内，两种临床参数均存在显着差异。姜黄素的局部施用还导致红色复合微生物的轻微至显著减少。
结论：本综述提示姜黄素局部应用可作为牙周炎机械清创的可行辅助手段。然而,需要进行进一步的研究以确定其最佳剂量，交货方式,以及获得最佳临床结果的频率。
方法：电子文献检索从PubMed，MEDLINE,和科学直接。筛选标题后，摘要,关键词和阅读这些文章，我们确定了9篇符合所有纳入标准的文章，包括在内进行系统审查。
结果：与对照组相比，在放置姜黄素片作为鳞屑和根部平整的辅助手段后的一个月内，两种临床参数均存在显着差异。姜黄素的局部施用还导致红色复合微生物的轻微至显著减少。
结论：本综述提示姜黄素局部应用可作为牙周炎机械清创的可行辅助手段。然而,需要进行进一步的研究以确定其最佳剂量，交货方式,以及获得最佳临床结果的频率。
