关键词: Pesticide exposure Primary headaches Prospective epidemiological research studies in Iran Rafsanjan cohort study

来  源:   DOI:10.1016/j.pmedr.2024.102621   PDF(Pubmed)

Abstract:
UNASSIGNED: Toxic substances can trigger headaches. The prevalence of pesticide use and headaches was high among the population of Rafsanjan.
UNASSIGNED: A cross-sectional study was used to collect data from 9991 adults who participated via sampling people aged 35-70 years old of both genders from the Rafsanjan Cohort Study (RCS) in Iran. Demographic characteristics, habits, chronic primary headache (CPH), and episodic primary headache (EPH) were measured.
UNASSIGNED: The prevalence of CPH and EPH were 7.4 % and 29.9 % respectively. The multivariable model showed the odds of EPH increased significantly by the pesticide exposure on farm OR: 1.16 (1.02-1.34), in yard OR: 1.18 (1.01-1.39), duration of pesticide exposure in yard > median OR: 1.35 (1.06-1.73), at home OR: 1.31 (1.17-1.46), duration of pesticide exposure at home ≤ median OR: 1.24 (1.10-1.40) and > median OR: 1.38 (1.22-1.57). Also, pesticide preparation OR: 1.20 (1.03-1.39), duration of exposure in pesticide preparation ≤ median OR: 1.31 (1.09-1.57), and duration of exposure in managed spraying pesticide > median OR: 1.28 (1.04-1.57) increased odds of EPH. These results showed that the odds of CPH increased in participants using pesticides at home OR: 1.22 (1.02-1.48), duration of pesticide exposure at home > median OR: 1.37 (1.11-1.70), and duration of pesticide exposure in pesticide preparation > median OR: 0.47 (0.27-0.82). The odds of EPH increased with more pesticide exposures (18 %) and duration of pesticide exposure (25 %).
UNASSIGNED: As evidenced by the obtained results, there is a relationship between pesticide exposure and headaches.
摘要:
有毒物质可引发头痛。在Rafsanjan人口中,农药使用和头痛的患病率很高。
一项横断面研究用于收集9991名成年人的数据,这些成年人通过对来自伊朗Rafsanjan队列研究(RCS)的35-70岁两种性别的人进行抽样。人口特征,习惯,慢性原发性头痛(CPH),测量发作性原发性头痛(EPH)。
CPH和EPH的患病率分别为7.4%和29.9%。多变量模型显示,农药暴露在农场或:1.16(1.02-1.34),码或:1.18(1.01-1.39),庭院农药暴露持续时间>中位数OR:1.35(1.06-1.73),在家或:1.31(1.17-1.46),家庭农药暴露持续时间≤中位数OR:1.24(1.10-1.40)和>中位数OR:1.38(1.22-1.57)。此外,农药制剂OR:1.20(1.03-1.39),农药制剂中的暴露持续时间≤中位数OR:1.31(1.09-1.57),管理喷洒农药的暴露持续时间>中位数OR:1.28(1.04-1.57)增加了发生EPH的几率。这些结果表明,在家中使用农药的参与者中,CPH的几率增加OR:1.22(1.02-1.48),家中农药暴露持续时间>中位数OR:1.37(1.11-1.70),农药制剂中农药暴露时间>中位数OR:0.47(0.27-0.82)。EPH的几率随着农药暴露(18%)和农药暴露持续时间(25%)的增加而增加。
所获得的结果证明,农药暴露和头痛之间有关系。
公众号