PDF(Pubmed)
Abstract：
UNASSIGNED: Increasing physical activity may prevent cognitive decline. Previous studies primarily focused on older adults and used self-reported questionnaires to assess physical activity. We examined the relationship between step count, an objective measure of physical activity, and cognitive function in community-based middle-aged and older Japanese men.
UNASSIGNED: The Shiga Epidemiological Study of Subclinical Atherosclerosis randomly recruited community-dwelling healthy men aged 40-79 years from Shiga, Japan, and measured their step counts over 7 consecutive days using a pedometer at baseline (2006-2008). Among men who returned for follow-up (2009-2014), we assessed their cognitive function using the Cognitive Abilities Screening Instrument (CASI) score. We restricted our analyses to those with valid 7-day average step counts at baseline and those who remained free of stroke at follow-up (n = 676). Using analysis of covariance, we calculated the adjusted means of the CASI score according to the quartiles of the average step counts.
UNASSIGNED: The mean (standard deviation) of age and unadjusted CASI score were 63.8 (9.1) years and 90.8 (5.8), respectively. The CASI score was elevated in higher quartiles of step counts (90.2, 90.4, 90.6, and 91.8 from the lowest to the highest quartile, respectively, [p for trend = 0.004]) in a model adjusted for age and education. Further adjustment for smoking, drinking, and other cardiovascular risk factors resulted in a similar pattern of association (p for trend = 0.005).
UNASSIGNED: In apparently healthy middle-aged and older Japanese men, a greater 7-day average step count at baseline was associated with significantly higher cognitive function score.
UNASSIGNED: The Shiga Epidemiological Study of Subclinical Atherosclerosis randomly recruited community-dwelling healthy men aged 40-79 years from Shiga, Japan, and measured their step counts over 7 consecutive days using a pedometer at baseline (2006-2008). Among men who returned for follow-up (2009-2014), we assessed their cognitive function using the Cognitive Abilities Screening Instrument (CASI) score. We restricted our analyses to those with valid 7-day average step counts at baseline and those who remained free of stroke at follow-up (n = 676). Using analysis of covariance, we calculated the adjusted means of the CASI score according to the quartiles of the average step counts.
UNASSIGNED: The mean (standard deviation) of age and unadjusted CASI score were 63.8 (9.1) years and 90.8 (5.8), respectively. The CASI score was elevated in higher quartiles of step counts (90.2, 90.4, 90.6, and 91.8 from the lowest to the highest quartile, respectively, [p for trend = 0.004]) in a model adjusted for age and education. Further adjustment for smoking, drinking, and other cardiovascular risk factors resulted in a similar pattern of association (p for trend = 0.005).
UNASSIGNED: In apparently healthy middle-aged and older Japanese men, a greater 7-day average step count at baseline was associated with significantly higher cognitive function score.
摘要：
■增加体力活动可以防止认知能力下降。以前的研究主要集中在老年人身上，并使用自我报告的问卷来评估身体活动。我们检查了步数之间的关系，身体活动的客观测量，以社区为基础的中老年日本男性的认知功能。
■志贺亚临床动脉粥样硬化的流行病学研究随机招募了来自志贺的40-79岁的社区居住健康男性，Japan,并在基线（2006-2008）使用计步器连续7天测量其步数。在返回随访的男性中（2009-2014年），我们使用认知能力筛查工具(CASI)评分评估他们的认知功能.我们将我们的分析限制在那些在基线时具有有效的7天平均步数的人和那些在随访时仍然没有中风的人(n=676)。使用协方差分析，我们根据平均步数的四分位数计算了CASI评分的调整平均值.
■年龄和未调整的CASI评分的平均值（标准偏差）分别为63.8（9.1）岁和90.8（5.8），分别。CASI分数在步数较高的四分位数中升高（从最低到最高四分位数90.2、90.4、90.6和91.8，分别,[趋势的p=0.004]）在针对年龄和教育程度进行调整的模型中。进一步调整吸烟，饮酒,和其他心血管危险因素导致相似的关联模式(趋势p=0.005).
■在明显健康的中老年日本男性中，基线时7日平均步数越多,认知功能评分越高.
■志贺亚临床动脉粥样硬化的流行病学研究随机招募了来自志贺的40-79岁的社区居住健康男性，Japan,并在基线（2006-2008）使用计步器连续7天测量其步数。在返回随访的男性中（2009-2014年），我们使用认知能力筛查工具(CASI)评分评估他们的认知功能.我们将我们的分析限制在那些在基线时具有有效的7天平均步数的人和那些在随访时仍然没有中风的人(n=676)。使用协方差分析，我们根据平均步数的四分位数计算了CASI评分的调整平均值.
■年龄和未调整的CASI评分的平均值（标准偏差）分别为63.8（9.1）岁和90.8（5.8），分别。CASI分数在步数较高的四分位数中升高（从最低到最高四分位数90.2、90.4、90.6和91.8，分别,[趋势的p=0.004]）在针对年龄和教育程度进行调整的模型中。进一步调整吸烟，饮酒,和其他心血管危险因素导致相似的关联模式(趋势p=0.005).
■在明显健康的中老年日本男性中，基线时7日平均步数越多,认知功能评分越高.
