关键词: basal cell adenoma benign oral mass histopathology minor salivary gland salivary gland tumor upper lip

来  源:   DOI:10.7759/cureus.52599   PDF(Pubmed)

Abstract:
Basal cell adenoma (BCA) is a rare, benign tumor originating from the epithelial cells of the salivary glands. It was earlier categorized as a subtype of monomorphic adenoma with distinctive histopathological features. BCA usually manifests as asymptomatic, slow-growing masses that exhibit a site and age predilection, commonly affecting the major salivary glands of elderly female patients. Histologically, solid, trabecular, tubular, and membranous patterns are recognized. It is imperative to establish a precise distinction between BCA, pleomorphic adenoma, and malignant salivary gland tumors before initiating treatment to ensure effective management. The standard treatment approach is surgical resection of the tumor. Recurrence and malignant transformation rarely occur, except for the membranous subtype. This article aims to report an unusual case of BCA arising from a minor salivary gland in the upper lip. The post-operative course was unremarkable, with complete healing of the surgical site. No recurrence was observed during a one-year follow-up. BCA arising from a minor salivary gland in the upper lip is an extremely uncommon entity. A comprehensive review of BCA in the upper lip, reported from 1991 to December 2023, revealed only 14 cases.
摘要:
基底细胞腺瘤(BCA)是一种罕见的,起源于唾液腺上皮细胞的良性肿瘤。较早被归类为具有独特组织病理学特征的单形性腺瘤的亚型。BCA通常表现为无症状,生长缓慢的肿块表现出部位和年龄偏好,通常影响老年女性患者的主要唾液腺。组织学上,固体,小梁,管状,膜状图案被识别。必须在BCA之间建立精确的区别,多形性腺瘤,和恶性唾液腺肿瘤开始治疗前,以确保有效的管理。标准治疗方法是手术切除肿瘤。复发和恶性转化很少发生,除了膜质亚型。本文旨在报告一例由上唇的小唾液腺引起的BCA异常病例。手术后的过程并不引人注目,手术部位完全愈合。在一年的随访中没有观察到复发。由上唇的小唾液腺引起的BCA是一种极为罕见的实体。全面回顾上唇的BCA,从1991年到2023年12月报告,只有14例。
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