VAV2 协调角质形成细胞和口腔鳞状细胞癌的再生增殖和核发生之间的相互作用。
关键词: Guanosine nucleotide exchange factors Oncogenic signaling PAK1 Patient prognosis Patient-derived cells RAC1 RHO GTPases RHOA RNA polymerase I ROCK Ribosomes YAP/TAZ
Mesh : Humans Carcinoma, Squamous Cell / pathology Cell Proliferation Head and Neck Neoplasms Keratinocytes / metabolism Mouth Neoplasms / genetics metabolism Proto-Oncogene Proteins c-vav / metabolism rho GTP-Binding Proteins / metabolism RNA Polymerase I / metabolism Squamous Cell Carcinoma of Head and Neck
来 源:
DOI:10.1038/s41598-024-54808-0
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