Abstract：
OBJECTIVE: This review will determine the prevalence and incidence of oral cancer and pre-cancerous lesions in indigenous populations.
BACKGROUND: There are approximately 476 million indigenous individuals worldwide. Oral cancer affected over 350,000 people globally in 2018, with approximately 80% of cases occurring in the indigenous population. Moreover, the incidence of pre-cancerous lesions is high in this population, accounting for 48.3%. Limited evidence exists regarding the burden of oral cancer among indigenous populations despite research on oral health disparities in this group.
METHODS: Studies on the burden of oral cancer and pre-cancerous lesions in indigenous groups, considering rates, ratios (prevalence or mortality), or survival proportions, will be considered for inclusion. There will be no limitations on study design, language, age, gender, or geography. We will exclude studies that only identify, diagnose, or screen oral cancer and pre-cancerous lesions without mentioning prevalence and incidence.
METHODS: This review will follow the JBI methodology for systematic reviews of prevalence and incidence. Databases to be searched will include MEDLINE (Ovid), Embase (Ovid), CINAHL (EBSCOhost), Cochrane Central Register of Controlled Trials, Scopus, and Dentistry and Oral Sciences Source (EBSCOhost). ProQuest Dissertations and Theses, OAIster, International Association for Dental Research conference abstracts, Google Scholar, government reports, and cancer registry reports will also be screened for unpublished studies. Two reviewers will independently screen articles, and data will be extracted using a customized form. Narrative data synthesis will be conducted and, where appropriate, meta-analysis will be performed. Methodological quality will be assessed using JBI\'s critical appraisal tool for prevalence studies.
BACKGROUND: PROSPERO CRD42023402858.
BACKGROUND: There are approximately 476 million indigenous individuals worldwide. Oral cancer affected over 350,000 people globally in 2018, with approximately 80% of cases occurring in the indigenous population. Moreover, the incidence of pre-cancerous lesions is high in this population, accounting for 48.3%. Limited evidence exists regarding the burden of oral cancer among indigenous populations despite research on oral health disparities in this group.
METHODS: Studies on the burden of oral cancer and pre-cancerous lesions in indigenous groups, considering rates, ratios (prevalence or mortality), or survival proportions, will be considered for inclusion. There will be no limitations on study design, language, age, gender, or geography. We will exclude studies that only identify, diagnose, or screen oral cancer and pre-cancerous lesions without mentioning prevalence and incidence.
METHODS: This review will follow the JBI methodology for systematic reviews of prevalence and incidence. Databases to be searched will include MEDLINE (Ovid), Embase (Ovid), CINAHL (EBSCOhost), Cochrane Central Register of Controlled Trials, Scopus, and Dentistry and Oral Sciences Source (EBSCOhost). ProQuest Dissertations and Theses, OAIster, International Association for Dental Research conference abstracts, Google Scholar, government reports, and cancer registry reports will also be screened for unpublished studies. Two reviewers will independently screen articles, and data will be extracted using a customized form. Narrative data synthesis will be conducted and, where appropriate, meta-analysis will be performed. Methodological quality will be assessed using JBI\'s critical appraisal tool for prevalence studies.
BACKGROUND: PROSPERO CRD42023402858.
摘要：
目的：本综述将确定土著人群中口腔癌和癌前病变的患病率和发病率。
背景：全世界大约有4.76亿土著人。2018年，口腔癌影响了全球超过35万人，其中约80％的病例发生在土著人口中。此外，在这个人群中，癌前病变的发生率很高，占48.3%。尽管对这一群体的口腔健康差异进行了研究，但关于土著居民口腔癌负担的证据有限。
方法：纳入标准涉及土著群体口腔癌和癌前病变负担的研究，考虑到利率，比率(患病率或死亡率)，或生存比例。数据库将从开始到现在进行搜索，对研究设计没有限制，语言,年龄,性别,或地理。我们将排除仅确定的研究，诊断,或筛查口腔癌和癌前病变而不提及患病率和发病率。
方法：本综述将遵循JBI方法对患病率和发病率进行系统评价。要搜索的数据库将包括MEDLINE(Ovid)，Embase(Ovid),CINAHL（EBSCOhost），Cochrane中央控制试验登记册,Scopus,和牙科和口腔科学来源（EBSCOhost）。ProQuest论文和论文，OAIster,国际牙科研究协会会议摘要，谷歌学者，政府报告,和癌症登记报告将筛选未发表的研究。两名审稿人将独立筛选文章，和数据将使用自定义表单提取。将进行叙事数据综合，在适当的情况下，使用JBISUMARI的荟萃分析。方法学质量将使用JBI的流行研究关键评估工具进行评估。
■PROSPEROCRD42023402858。
背景：全世界大约有4.76亿土著人。2018年，口腔癌影响了全球超过35万人，其中约80％的病例发生在土著人口中。此外，在这个人群中，癌前病变的发生率很高，占48.3%。尽管对这一群体的口腔健康差异进行了研究，但关于土著居民口腔癌负担的证据有限。
方法：纳入标准涉及土著群体口腔癌和癌前病变负担的研究，考虑到利率，比率(患病率或死亡率)，或生存比例。数据库将从开始到现在进行搜索，对研究设计没有限制，语言,年龄,性别,或地理。我们将排除仅确定的研究，诊断,或筛查口腔癌和癌前病变而不提及患病率和发病率。
方法：本综述将遵循JBI方法对患病率和发病率进行系统评价。要搜索的数据库将包括MEDLINE(Ovid)，Embase(Ovid),CINAHL（EBSCOhost），Cochrane中央控制试验登记册,Scopus,和牙科和口腔科学来源（EBSCOhost）。ProQuest论文和论文，OAIster,国际牙科研究协会会议摘要，谷歌学者，政府报告,和癌症登记报告将筛选未发表的研究。两名审稿人将独立筛选文章，和数据将使用自定义表单提取。将进行叙事数据综合，在适当的情况下，使用JBISUMARI的荟萃分析。方法学质量将使用JBI的流行研究关键评估工具进行评估。
■PROSPEROCRD42023402858。
