PDF(Pubmed)
Abstract：
UNASSIGNED: Hypokalaemia (K+<3.5 mmol/L) is observed in 20% of hospitalised patients. Previous studies have often dealt with the symptoms, prevalence and risk factors in hospitalised patients. Very few studies have dealt with hospital-induced hypokalaemia. The aim was to determine the incidence, predisposing risk factors and prognosis of patients developing hypokalaemia after admission.
UNASSIGNED: A prospective observational study was performed for two months. Patients with at least two potassium values after admission and normal K values at admission were considered for inclusion. Clinical features, diagnoses, laboratory reports and treatment details, including antibiotics, were noted.
UNASSIGNED: A total of 653 patients were studied; 138 (21.1%) developed hypokalaemia. Diabetes, ischaemic heart disease (IHD), heart failure, chronic kidney disease, hypertension, chronic liver disease and chronic obstructive pulmonary disease (COPD) were the most associated comorbidities. Urea, creatinine, transaminases and neutrophilia at admission differed significantly between those with and without hypokalaemia groups. Most patients developed mild hypokalaemia (78.2%). Hypokalaemia developed mostly on the second (22.4%) and third (24.6%) days of hospitalisation. Antibiotics were used in 60% of patients. The potassium values returned to normal within 2.5 ± 1.9 days. Three patients subsequently developed hyperkalaemia.
UNASSIGNED: Patients admitted under general medicine mostly developed mild hypokalaemia, even if they had multiple risk factors for developing hypokalaemia. Inpatient hypokalaemia had an incidence of 21%. An overwhelming majority (~88%) had at least one risk factor. Hypokalaemia was not attributed to causing mortality in any patient.
UNASSIGNED: A prospective observational study was performed for two months. Patients with at least two potassium values after admission and normal K values at admission were considered for inclusion. Clinical features, diagnoses, laboratory reports and treatment details, including antibiotics, were noted.
UNASSIGNED: A total of 653 patients were studied; 138 (21.1%) developed hypokalaemia. Diabetes, ischaemic heart disease (IHD), heart failure, chronic kidney disease, hypertension, chronic liver disease and chronic obstructive pulmonary disease (COPD) were the most associated comorbidities. Urea, creatinine, transaminases and neutrophilia at admission differed significantly between those with and without hypokalaemia groups. Most patients developed mild hypokalaemia (78.2%). Hypokalaemia developed mostly on the second (22.4%) and third (24.6%) days of hospitalisation. Antibiotics were used in 60% of patients. The potassium values returned to normal within 2.5 ± 1.9 days. Three patients subsequently developed hyperkalaemia.
UNASSIGNED: Patients admitted under general medicine mostly developed mild hypokalaemia, even if they had multiple risk factors for developing hypokalaemia. Inpatient hypokalaemia had an incidence of 21%. An overwhelming majority (~88%) had at least one risk factor. Hypokalaemia was not attributed to causing mortality in any patient.
摘要：
■在20%的住院患者中观察到低钾血症(K+<3.5mmol/L)。以前的研究经常涉及症状，住院患者的患病率和危险因素。很少有研究涉及医院引起的低钾血症。目的是确定发病率，入院后发生低钾血症患者的易感危险因素和预后。
■进行了为期两个月的前瞻性观察性研究。考虑纳入入院后至少有两个钾值和入院时正常K值的患者。临床特征,诊断,实验室报告和治疗细节，包括抗生素,被注意到。
■共研究653例患者；138例（21.1%）出现低钾血症。糖尿病,缺血性心脏病（IHD），心力衰竭,慢性肾病,高血压,慢性肝病和慢性阻塞性肺疾病(COPD)是最相关的合并症.尿素,肌酐,在有低钾血症和无低钾血症组患者之间,入院时转氨酶和嗜中性粒细胞有显著差异.大多数患者出现轻度低钾血症（78.2%）。低钾血症主要发生在住院的第二天（22.4％）和第三天（24.6％）。60%的患者使用抗生素。钾值在2.5±1.9天内恢复正常。三名患者随后发展为高钾血症。
■接受普通医学治疗的患者大多出现轻度低钾血症，即使他们有多种发生低钾血症的危险因素。住院患者低钾血症的发生率为21％。绝大多数（约88％）至少有一个危险因素。低钾血症并不是导致任何患者死亡的原因。
■进行了为期两个月的前瞻性观察性研究。考虑纳入入院后至少有两个钾值和入院时正常K值的患者。临床特征,诊断,实验室报告和治疗细节，包括抗生素,被注意到。
■共研究653例患者；138例（21.1%）出现低钾血症。糖尿病,缺血性心脏病（IHD），心力衰竭,慢性肾病,高血压,慢性肝病和慢性阻塞性肺疾病(COPD)是最相关的合并症.尿素,肌酐,在有低钾血症和无低钾血症组患者之间,入院时转氨酶和嗜中性粒细胞有显著差异.大多数患者出现轻度低钾血症（78.2%）。低钾血症主要发生在住院的第二天（22.4％）和第三天（24.6％）。60%的患者使用抗生素。钾值在2.5±1.9天内恢复正常。三名患者随后发展为高钾血症。
■接受普通医学治疗的患者大多出现轻度低钾血症，即使他们有多种发生低钾血症的危险因素。住院患者低钾血症的发生率为21％。绝大多数（约88％）至少有一个危险因素。低钾血症并不是导致任何患者死亡的原因。
