关键词: adult-onset benign cutaneous myofibroma infantile myofibroma multifocal multifocal infantile myofibroma myofibromas myofibromatosis smooth-muscle actin

来  源:   DOI:10.7759/cureus.52438   PDF(Pubmed)

Abstract:
Myofibromas are observed in both infantile and adult presentations, with key differences in the number and severity of lesions between these two groups. Infantile presentations encompass both indolent, isolated cutaneous lesions, as well as aggressive, multicentric presentations with visceral involvement. Adult myofibromas appear to be characterized by a single isolated cutaneous lesion, generally asymptomatic and following a benign clinical course. The occurrence of adult multifocal myofibromas has not yet been described in the literature. Here, we report a case of a 57-year-old female who presented with two minimally symptomatic soft tissue lesions on her right leg, with the pathologic findings of each lesion consistent with a cutaneous myofibroma. This case report describes a rare presentation of adult-onset multifocal cutaneous myofibromas.
摘要:
肌纤维瘤在婴儿和成人表现中都观察到,这两组在病变的数量和严重程度上存在关键差异。婴儿期的介绍既包括惰性,孤立的皮肤病变,以及侵略性,内脏受累的多中心表现。成人肌纤维瘤的特征似乎是单个孤立的皮肤病变,通常无症状且遵循良性临床过程。成人多灶性肌纤维瘤的发生尚未在文献中描述。这里,我们报告了一例57岁的女性,她的右腿上有两个症状轻微的软组织病变,每个病变的病理结果与皮肤肌纤维瘤一致。此病例报告描述了成人发作的多灶性皮肤肌纤维瘤的罕见表现。
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