PDF(Pubmed)
Abstract：
UNASSIGNED: To determine short-term morbidity and mortality rates in the first state-wide Austrian neonatal cohort and comparison to (inter)national data.
UNASSIGNED: Observational, population-based cohort study, analyzing data of preterm infants (<32 + 0 weeks of gestation) born between 2007 and 2020 (n = 501) in an Austrian state who were admitted to the neonatal intensive care unit. Outcome criteria were mortality, neonatal morbidities: bronchopulmonary dysplasia (BPD), severe necrotizing enterocolitis (NEC), severe intraventricular hemorrhage (IVH grades III-IV), severe retinopathy of prematurity (ROP grades III-V) and survival-free of major complications.
UNASSIGNED: Overall survival rate was 95%, survival free of major complications was 79%. Prevalence for BPD was 11.2%, surgical NEC 4.0%, severe IVH 4.6%, and for severe ROP 2.6%, respectively. In the extremely low gestational age neonates (ELGAN) born <28 weeks of gestation (n = 158), survival was 88% and survival free of major complications 58.8%. Over time, mortality decreased significantly, predominantly driven by the improvement of infants born <28 week of gestation and survival free of major complications improved.
UNASSIGNED: This study demonstrates a very low mortality rate that decreases over time. Short-term morbidities and survival free of major complications do not differ from (inter)national data in a similar group of very preterm infants. Standard operating procedures, simulation trainings and accordance to international trials may improve patient care and surpass center case loads.
UNASSIGNED: Observational, population-based cohort study, analyzing data of preterm infants (<32 + 0 weeks of gestation) born between 2007 and 2020 (n = 501) in an Austrian state who were admitted to the neonatal intensive care unit. Outcome criteria were mortality, neonatal morbidities: bronchopulmonary dysplasia (BPD), severe necrotizing enterocolitis (NEC), severe intraventricular hemorrhage (IVH grades III-IV), severe retinopathy of prematurity (ROP grades III-V) and survival-free of major complications.
UNASSIGNED: Overall survival rate was 95%, survival free of major complications was 79%. Prevalence for BPD was 11.2%, surgical NEC 4.0%, severe IVH 4.6%, and for severe ROP 2.6%, respectively. In the extremely low gestational age neonates (ELGAN) born <28 weeks of gestation (n = 158), survival was 88% and survival free of major complications 58.8%. Over time, mortality decreased significantly, predominantly driven by the improvement of infants born <28 week of gestation and survival free of major complications improved.
UNASSIGNED: This study demonstrates a very low mortality rate that decreases over time. Short-term morbidities and survival free of major complications do not differ from (inter)national data in a similar group of very preterm infants. Standard operating procedures, simulation trainings and accordance to international trials may improve patient care and surpass center case loads.
摘要：
■确定第一个全州奥地利新生儿队列中的短期发病率和死亡率，并与（国家间）数据进行比较。
■观测，基于人群的队列研究，分析2007年至2020年(n=501)在奥地利出生的早产儿(<32+0孕周)的数据,这些早产儿被送入新生儿重症监护病房.结果标准是死亡率，新生儿发病率：支气管肺发育不良（BPD），严重坏死性小肠结肠炎（NEC），严重脑室内出血（IVHIII-IV级），严重的早产儿视网膜病变（ROPIII-V级）和无主要并发症的生存。
■总生存率为95%，无主要并发症的生存率为79%.BPD的患病率为11.2%,外科NEC4.0%，严重IVH4.6%，对于严重的ROP2.6%，分别。在出生<28周的极低胎龄新生儿（ELGAN）（n=158），生存率为88%,无主要并发症生存率为58.8%.随着时间的推移,死亡率显著下降，主要由出生<28孕周的婴儿的改善和无主要并发症的存活率改善。
■这项研究表明，死亡率非常低，并且随着时间的推移而下降。短期发病率和无主要并发症的生存率与类似的极早产儿组的（国际）国家数据没有差异。标准操作程序，模拟培训和根据国际试验可以改善病人护理和超越中心病例负荷。
■观测，基于人群的队列研究，分析2007年至2020年(n=501)在奥地利出生的早产儿(<32+0孕周)的数据,这些早产儿被送入新生儿重症监护病房.结果标准是死亡率，新生儿发病率：支气管肺发育不良（BPD），严重坏死性小肠结肠炎（NEC），严重脑室内出血（IVHIII-IV级），严重的早产儿视网膜病变（ROPIII-V级）和无主要并发症的生存。
■总生存率为95%，无主要并发症的生存率为79%.BPD的患病率为11.2%,外科NEC4.0%，严重IVH4.6%，对于严重的ROP2.6%，分别。在出生<28周的极低胎龄新生儿（ELGAN）（n=158），生存率为88%,无主要并发症生存率为58.8%.随着时间的推移,死亡率显著下降，主要由出生<28孕周的婴儿的改善和无主要并发症的存活率改善。
■这项研究表明，死亡率非常低，并且随着时间的推移而下降。短期发病率和无主要并发症的生存率与类似的极早产儿组的（国际）国家数据没有差异。标准操作程序，模拟培训和根据国际试验可以改善病人护理和超越中心病例负荷。
