关键词: Breast cancer Breast surgery Case report Multidisciplinary team Renal cell cancer Synchronous primary cancers

来  源:   DOI:10.1016/j.ijscr.2024.109400   PDF(Pubmed)

Abstract:
BACKGROUND: Multiple primary cancers (MPCs) have attracted attention in medical research due to their increasing incidence. The coexistence of invasive breast carcinoma and clear cell carcinoma of the kidney, alongside a family history of cancer, highlights the multifactorial origins of MPCs, particularly their potential association with genetic factors.
METHODS: A 70-year-old female initially sought medical attention for a two-year history of a right breast lump as her primary concerns centered on the long-standing lump. Clinical evaluations and imaging studies revealed an invasive breast carcinoma diagnosis, and simultaneously, an incidental mass in her left kidney was identified as clear cell carcinoma.
CONCLUSIONS: Emphasis and further researh should be on the potential role of genetic factors in MPC development, necessitating comprehensive genetic evaluations.
CONCLUSIONS: This study highlights the significance of customized treatment approaches for each malignancy, facilitating early detection, improved patient outcomes, and an enhanced understanding of MPCs.
摘要:
背景:多原发癌(MPC)由于其发病率的增加而在医学研究中引起了关注。浸润性乳腺癌与肾透明细胞癌并存,还有家族癌症史,突出了MPC的多因素起源,特别是它们与遗传因素的潜在关联。
方法:一名70岁的女性最初寻求医疗护理,因为她的主要问题集中在长期的肿块上。临床评估和影像学研究显示浸润性乳腺癌诊断,同时,她的左肾偶发肿块被确定为透明细胞癌。
结论:重点和进一步的研究应该是遗传因素在MPC发育中的潜在作用。需要全面的遗传评估。
结论:这项研究强调了定制治疗方法对每种恶性肿瘤的重要性,促进早期检测,改善患者预后,增强对MPC的理解。
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