METHODS: An electronic search of three databases (PubMed, Cochrane, and Embase) and a manual search of relevant articles published up to May 2023 were carried out. Clinical trials (≥ 10 subjects) that utilized surgically facilitated orthodontic strategies with clinical and/or radiographic outcomes were included. Meta-analyses and sub-group analyses were performed to analyze the standardized mean difference (SMD) or weighted mean difference (WMD), and confidence interval (CI) for the recorded variables.
RESULTS: Nineteen studies published from Oct 2012 to May 2023 met the inclusion criteria. Based on the analysis outcomes, corticotomy treatment significantly decreased the alignment duration (WMD: -1.08 months; 95% CI = -1.65, -0.51 months, P = 0.0002), and accelerated the canine movement (WMD: 0.72 mm; 95% CI = 0.63, 0.81 mm, P < 0.00001) compared to the traditional orthodontic group. The periodontally accelerated osteogenic orthodontic (PAOO) strategy markedly reduced the total treatment duration (SMD: -1.98; 95% CI = -2.59, -1.37, P < 0.00001) and increased the bone thickness (SMD:1.07; 95% CI = 0.74, 1.41, P < 0.00001) compared to traditional orthodontic treatment.
CONCLUSIONS: The present study suggests that facilitated orthodontic treatment in terms of corticotomy and PAOO strategy may represent attractive and effective therapeutic strategy for orthodontic patients.
方法:对三个数据库进行电子搜索(PubMed,科克伦,和Embase),并对截至2023年5月发表的相关文章进行了手动搜索。包括使用具有临床和/或影像学结果的手术促进的正畸策略的临床试验(≥10名受试者)。进行Meta分析和亚组分析,分析标准化均差(SMD)或加权均差(WMD),以及记录变量的置信区间(CI)。
结果:2012年10月至2023年5月发表的19项研究符合纳入标准。根据分析结果,皮质切开术治疗显着缩短了对准持续时间(WMD:-1.08个月;95%CI=-1.65,-0.51个月,P=0.0002),并加速了犬的运动(WMD:0.72mm;95%CI=0.63,0.81mm,P<0.00001)与传统正畸组比拟。与传统正畸治疗相比,牙周加速成骨正畸(PAOO)策略显着缩短了总治疗时间(SMD:-1.98;95%CI=-2.59,-1.37,P<0.00001),并增加了骨厚度(SMD:1.07;95%CI=0.74,1.41,P<0.00001)。
结论:本研究表明,在皮质切开术和PAOO策略方面,促进正畸治疗可能是正畸患者有吸引力和有效的治疗策略。