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Abstract：
BACKGROUND: The surgically facilitated orthodontic strategy has been a promising strategy for orthodontic treatment recently. Therefore, the present meta-analysis was conducted to assess the available scientific evidence regarding the clinical outcomes, including the potential detrimental effects associated with these surgical procedures, with the aim of providing much more evidence-based information for clinical practice.
METHODS: An electronic search of three databases (PubMed, Cochrane, and Embase) and a manual search of relevant articles published up to May 2023 were carried out. Clinical trials (≥ 10 subjects) that utilized surgically facilitated orthodontic strategies with clinical and/or radiographic outcomes were included. Meta-analyses and sub-group analyses were performed to analyze the standardized mean difference (SMD) or weighted mean difference (WMD), and confidence interval (CI) for the recorded variables.
RESULTS: Nineteen studies published from Oct 2012 to May 2023 met the inclusion criteria. Based on the analysis outcomes, corticotomy treatment significantly decreased the alignment duration (WMD: -1.08 months; 95% CI = -1.65, -0.51 months, P = 0.0002), and accelerated the canine movement (WMD: 0.72 mm; 95% CI = 0.63, 0.81 mm, P < 0.00001) compared to the traditional orthodontic group. The periodontally accelerated osteogenic orthodontic (PAOO) strategy markedly reduced the total treatment duration (SMD: -1.98; 95% CI = -2.59, -1.37, P < 0.00001) and increased the bone thickness (SMD:1.07; 95% CI = 0.74, 1.41, P < 0.00001) compared to traditional orthodontic treatment.
CONCLUSIONS: The present study suggests that facilitated orthodontic treatment in terms of corticotomy and PAOO strategy may represent attractive and effective therapeutic strategy for orthodontic patients.
METHODS: An electronic search of three databases (PubMed, Cochrane, and Embase) and a manual search of relevant articles published up to May 2023 were carried out. Clinical trials (≥ 10 subjects) that utilized surgically facilitated orthodontic strategies with clinical and/or radiographic outcomes were included. Meta-analyses and sub-group analyses were performed to analyze the standardized mean difference (SMD) or weighted mean difference (WMD), and confidence interval (CI) for the recorded variables.
RESULTS: Nineteen studies published from Oct 2012 to May 2023 met the inclusion criteria. Based on the analysis outcomes, corticotomy treatment significantly decreased the alignment duration (WMD: -1.08 months; 95% CI = -1.65, -0.51 months, P = 0.0002), and accelerated the canine movement (WMD: 0.72 mm; 95% CI = 0.63, 0.81 mm, P < 0.00001) compared to the traditional orthodontic group. The periodontally accelerated osteogenic orthodontic (PAOO) strategy markedly reduced the total treatment duration (SMD: -1.98; 95% CI = -2.59, -1.37, P < 0.00001) and increased the bone thickness (SMD:1.07; 95% CI = 0.74, 1.41, P < 0.00001) compared to traditional orthodontic treatment.
CONCLUSIONS: The present study suggests that facilitated orthodontic treatment in terms of corticotomy and PAOO strategy may represent attractive and effective therapeutic strategy for orthodontic patients.
摘要：
背景：手术促进的正畸治疗策略最近已成为一种有希望的正畸治疗策略。因此,本荟萃分析旨在评估有关临床结局的现有科学证据，包括与这些外科手术相关的潜在有害影响，目的是为临床实践提供更多的循证信息。
方法：对三个数据库进行电子搜索（PubMed，科克伦,和Embase），并对截至2023年5月发表的相关文章进行了手动搜索。包括使用具有临床和/或影像学结果的手术促进的正畸策略的临床试验（≥10名受试者）。进行Meta分析和亚组分析，分析标准化均差（SMD）或加权均差（WMD），以及记录变量的置信区间(CI)。
结果：2012年10月至2023年5月发表的19项研究符合纳入标准。根据分析结果，皮质切开术治疗显着缩短了对准持续时间（WMD：-1.08个月；95％CI=-1.65，-0.51个月，P=0.0002),并加速了犬的运动（WMD：0.72mm；95％CI=0.63，0.81mm，P<0.00001)与传统正畸组比拟。与传统正畸治疗相比，牙周加速成骨正畸（PAOO）策略显着缩短了总治疗时间（SMD：-1.98；95％CI=-2.59，-1.37，P<0.00001），并增加了骨厚度（SMD：1.07；95％CI=0.74，1.41，P<0.00001）。
结论：本研究表明，在皮质切开术和PAOO策略方面，促进正畸治疗可能是正畸患者有吸引力和有效的治疗策略。
方法：对三个数据库进行电子搜索（PubMed，科克伦,和Embase），并对截至2023年5月发表的相关文章进行了手动搜索。包括使用具有临床和/或影像学结果的手术促进的正畸策略的临床试验（≥10名受试者）。进行Meta分析和亚组分析，分析标准化均差（SMD）或加权均差（WMD），以及记录变量的置信区间(CI)。
结果：2012年10月至2023年5月发表的19项研究符合纳入标准。根据分析结果，皮质切开术治疗显着缩短了对准持续时间（WMD：-1.08个月；95％CI=-1.65，-0.51个月，P=0.0002),并加速了犬的运动（WMD：0.72mm；95％CI=0.63，0.81mm，P<0.00001)与传统正畸组比拟。与传统正畸治疗相比，牙周加速成骨正畸（PAOO）策略显着缩短了总治疗时间（SMD：-1.98；95％CI=-2.59，-1.37，P<0.00001），并增加了骨厚度（SMD：1.07；95％CI=0.74，1.41，P<0.00001）。
结论：本研究表明，在皮质切开术和PAOO策略方面，促进正畸治疗可能是正畸患者有吸引力和有效的治疗策略。
