Abstract：
The aim of this study was to evaluate the clinical efficacy of alcohol-based therapy for patients with large odontogenic keratocysts (OKCs). The study was implemented as a retrospective, single-center study. Patients treated with ethanol-based therapy for odontogenic keratocyst were retrospectively evaluated for baseline and postoperative data. The pre- and postoperative clinical situation and the extent of radiographic shrinkage were compared. The event is defined as the achievement of >50% reduction in cyst volume. The cyst reduction rate calculated on panoramic radiographs ranged from 7.4% to 99.9% (mean [standard deviation] 55.3% [27.9%]) and was statistically significant (P < 0.05). Specifically, it has been found that, radiographically, 47.6% of patients achieved >50% reduction in cyst volume within 12 months. The continuous cortical bone was rebuilt, and the cyst cavity was filled with regenerated trabecular bone. The 22 included patients presented with nonclinical problems, had no need for further intervention, and exhibited persistent impaction of the teeth. The results of this study demonstrated that ethanol-based therapy triggered marked radiographic reductions of large OKC, indicating that using this technique is efficient.
摘要：
这项研究的目的是评估基于酒精的治疗对大型牙源性角化囊肿（OKCs）患者的临床疗效。这项研究是一项回顾性研究，单中心研究。对使用乙醇治疗牙源性角化囊肿的患者进行基线和术后数据的回顾性评估。比较术前和术后的临床情况以及影像学收缩的程度。该事件定义为囊肿体积减少>50%。全景X线片计算的囊肿缩小率为7.4％至99.9％（平均值[标准偏差]55.3％[27.9％]），具有统计学意义（P<0.05）。具体来说,已经发现,射线照相，47.6％的患者在12个月内囊肿体积减少>50％。重建了连续的皮质骨，囊肿腔内充满了再生骨小梁。这22名患者出现了非临床问题，不需要进一步干预，并表现出持续的牙齿撞击。这项研究的结果表明，以乙醇为基础的治疗引发了大OKC的显着放射学减少，这表明使用这种技术是有效的。
