关键词: Gastric schwannoma Immunochemical staining Neurolemmas S 100 positive Schwann cell

来  源:   DOI:10.1016/j.ijscr.2024.109389   PDF(Pubmed)

Abstract:
UNASSIGNED: Gastric schwannoma is a rare and benign tumor originating from the peripheral nerves of the stomach. Despite its benign nature, this tumor typically remains asymptomatic for an extended period, and its radiological and endoscopic presentation poses challenges in distinguishing it from other gastric mesenchymal tumors.
METHODS: Here, we present a rare case of a patient experiencing gastric pain and melena secondary to a gastric mass. The initial preoperative diagnosis indicated a gastrointestinal stromal tumor, but subsequent pathological and immunohistochemical staining of the surgical specimen confirmed the presence of gastric schwannoma.
CONCLUSIONS: To gain insights into this uncommon condition, we conducted an electronic search on PubMed using the keywords \"gastric schwannoma\" and \"gastric neurinoma.\" Our focus centered on case series containing more than five cases of gastric localization, resulting in the analysis of 14 case series involving a total of 321 patients. Our review aims to comprehensively discuss the clinical, radiological, and therapeutic aspects associated with this rare disease.
CONCLUSIONS: In the absence of a definitive preoperative diagnosis, the surgical approach is considered the primary treatment for resectable gastric schwannoma, given its excellent long-term outcomes. However, further studies are imperative to better define the role of endoscopic resection in managing this condition.
摘要:
胃神经鞘瘤是一种罕见的良性肿瘤,起源于胃的周围神经。尽管它是良性的,这种肿瘤通常长时间无症状,其放射学和内窥镜表现在将其与其他胃间充质肿瘤区分开来方面提出了挑战。
方法:这里,我们介绍了一例罕见的患者,该患者经历了继发于胃肿块的胃痛和黑便。术前初步诊断为胃肠道间质瘤,但随后手术标本的病理和免疫组织化学染色证实存在胃神经鞘瘤。
结论:为了深入了解这种罕见的情况,我们使用关键词“胃神经鞘瘤”和“胃神经鞘瘤”对PubMed进行了电子搜索。“我们的重点集中在包含超过五例胃定位的病例系列上,结果分析了14例病例系列,共321例患者。我们的综述旨在全面讨论临床,放射学,以及与这种罕见疾病相关的治疗方面。
结论:在没有明确的术前诊断的情况下,手术方法被认为是可切除的胃神经鞘瘤的主要治疗方法,鉴于其出色的长期结果。然而,进一步的研究是必要的,以更好地确定内镜切除术在治疗这种情况中的作用.
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