关键词: HIV Menopausal hormone therapy Menopausal management guidelines Menopausal symptoms Menopause

Mesh : Female Humans HIV Menopause HIV Infections / complications drug therapy

来  源:   DOI:10.1016/j.maturitas.2024.107937

Abstract:
Women living with human immunodeficiency virus (HIV) today have life expectancies comparable to the general female population, leading to a growing number transitioning through menopause. Recent studies have highlighted healthcare professionals\' lack of confidence in managing menopause in women with HIV, raising concerns about potential mismanagement. This review explores and compares information on menopause management in HIV-specific and general guidelines, with the aim of identifying disparities and assessing the comprehensiveness of HIV guidelines. The focus is on three key areas: the diagnosis of menopause, and the assessment and treatment of menopausal symptoms. Additionally, the review evaluates the usage and characteristics of menopausal symptom assessment scales known to have been used in studies involving women living with HIV. In total, five HIV and six general menopause management guidelines, published between 2015 and 2023, were identified through medical databases, internet search engines and searches of reference lists. Five menopausal symptom assessment scales were also included for review. The findings suggest minimal differences in recommendations for treating menopausal symptoms. The HIV guidelines include recommendations on screening for menopause, and some raise awareness of the possibility of drug-to-drug interactions, but none offers guidance on how to diagnose menopause or how to differentiate between HIV-related and menopause-related symptoms. Upon examining the characteristics of the menopausal symptom assessment scales, we found that none had been validated specifically for women with HIV. In conclusion, this review advocates for the development of a comprehensive guideline that addresses all relevant factors in managing menopause in women with HIV.
摘要:
今天,患有人类免疫缺陷病毒(HIV)的妇女的预期寿命与普通女性人口相当,导致越来越多的人通过更年期过渡。最近的研究表明,医疗保健专业人员对管理HIV感染女性更年期缺乏信心,引发对潜在管理不善的担忧。这篇综述探讨并比较了HIV特异性指南和一般指南中有关更年期管理的信息。目的是确定差距并评估艾滋病毒准则的全面性。重点是三个关键领域:更年期的诊断,以及更年期症状的评估和治疗。此外,本综述评估了已知用于HIV感染女性研究的更年期症状评估量表的用法和特点.总的来说,五项艾滋病毒和六项一般更年期管理指南,在2015年至2023年之间发布,通过医学数据库确定,互联网搜索引擎和参考列表的搜索。还包括五个更年期症状评估量表进行审查。研究结果表明,治疗更年期症状的建议差异很小。艾滋病毒指南包括对更年期筛查的建议,一些人提高了人们对药物相互作用可能性的认识,但是没有提供关于如何诊断更年期或如何区分HIV相关症状和更年期相关症状的指导。在检查更年期症状评估量表的特征后,我们发现,对于感染HIV的女性,均未得到特别验证.总之,本综述主张制定一项综合指南,解决HIV感染女性更年期管理的所有相关因素.
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